Glutathione, Cysteine & C

Category: Antioxidants


Powerful intracellular antioxidant support

  • Cysteine plays a role in phase II detoxification and in the conversion of homocysteine to methionine

  • Cysteine also helps synthesize glutathione

  • Glutathione is one of the body’s most important and powerful antioxidants

  • A major function of vitamin C is to keep glutathione in its reduced form so that it can continue to provide free radical-quenching effects

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Glutathione, Cysteine & C

100 vegetarian capsules

Item Catalog Number: 01541

NON GMO ProductL-cysteine is a conditionally essential amino acid, one of only three sulfur-containing amino acids, the others being taurine (which can be produced from L-cysteine) and L-methionine (from which L-cysteine can be produced in the body by a multi-step process). Cysteine plays a role in the sulfation cycle, acting as a sulfur donor in phase II detoxification and as a methyl donor in the conversion of homocysteine to methionine.1-3 Cysteine also helps synthesize glutathione, the body’s most important intracellular antioxidant and a vital detoxifier.4-7

Glutathione (L-gamma-glutamyl-L-cysteinyl-glycine) is a peptide molecule synthesized in the body from the three amino acids L-glutamic acid, L-cysteine, and glycine. Glutathione is one of the body’s most important and powerful antioxidants,8 helping to detoxify xenobiotics.9-12 A major function of vitamin C is to keep glutathione in its reduced form so that it can continue to provide free radical-quenching effects.13-16

Vitamin C, or ascorbic acid, is a white, crystalline, water-soluble substance found in citrus fruits. As an antioxidant, vitamin C scavenges free radicals in the body and protects tissues from oxidative stress.17-24 Vitamin C also promotes the absorption of iron, while inhibiting its oxidation.25,26 Vitamin C is a vital cofactor in the formation of collagen, the connective tissue that supports arterial walls, skin, bones, and teeth.20-22

Supplement Facts

Serving Size 1 vegetarian capsule

Amount Per Serving
Vitamin C (as ascorbic acid) 500 mg
Setria® L-Glutathione (reduced) 50 mg
L-Cysteine Hydrochloride 200 mg
Other ingredients: vegetable cellulose (capsule), rice bran, microcrystalline cellulose, silica.


Setria® is a registered trademark of KYOWA HAKKO BIO Co., Ltd.

Dosage and Use

Take one (1) capsule one to three times daily on an empty stomach, or as recommended by a healthcare practitioner.




Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

  1. Mol Pathol. 2003 Oct;56(5):270-4.

  2. Eur J Hum Genet. 2003 Jan;11(1):23-9.

  3. Acta Biochim Pol. 2004;51(2):405-13.

  4. Biol Chem. 2009 Mar;390(3):191-214.

  5. Aviat Space Environ Med. 2008 Dec;79(12):1106-11.

  6. Int J Gen Med. 2011 Jan 25;4:105-13.

  7. Cardiovasc Toxicol. 2011 Mar;11(1):1-9.

  8. Antioxid Redox Signal. 2011 Oct 1;15(7):1957-97.

  9. Mutat Res. 2005 Dec 11;591(1-2):74-92.

  10. FEBS Lett. 2005 Aug 1;579(19):4081-7.

  11. FEBS J. 2009 Jan;276(1):58-75.

  12. Toxicol Sci. 2007 Dec;100(2):513-24. Epub 2007 Sep 22.

  13. Clin Chim Acta. 2003 Jan;327(1-2):187-8.

  14. Proc Natl Acad Sci USA. 1991 Jun 1;88(11):4656-60.

  15. Plant Physiol. 2011 Jan;155(1):2-18.

  16. Am J Clin Nutr. 2000 May;71(5):1194-200.

  17. Biochim Biophys Acta. 2012 Dec;1826(2):443-57.

  18. Redox Rep. 2010;15(1):11-9.

  19. Adv Nutr. 2011 Mar;2(2):78-88.

  20. Altern Med Rev. 2003 Nov;8(4):359-77.

  21. J Invest Dermatol. 2002 Apr;118(4):565-72.

  22. Radiat Environ Biophys. 2007 Mar;46(1):61-8.

  23. Free Radic Biol Med. 2007 Sep 1;43(5):853-9.

  24. PLoS Negl Trop Dis. 2012;6(7):e1729.

  25. Br J Nutr. 2003 Dec;90(6):1081-5.

  26. Am J Clin Nutr. 2006 Oct;84(4):830-4.

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