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SOD Booster

Category: Antioxidants

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Helps protect cells from cellular stress

  • Promotes SOD (superoxide dismutase) production
  • Helps the body inhibit cellular stress caused by free radicals
  • Promotes healthy longevity and cellular function

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SOD Booster 

30 vegetarian capsules

Item Catalog Number: 02361

NON GMO Product

The body makes its own antioxidant enzymes: glutathione, catalase and importantly, superoxide dismutase. This powerhouse antioxidant helps protect your cells from cellular stress caused by free radicals.1 Cellular stress can increase the process of natural aging—and levels of superoxide dismutase production have been shown to decrease with age.2 That’s why we created our dual-ingredient SOD Booster formula.

Benefits at a Glance:

  • Promotes SOD (superoxide dismutase) production
  • Helps the body inhibit cellular stress caused by free radicals
  • Promotes healthy longevity and cellular function

Chokeberry (A. melanocarpa) Extract

Chokeberries have one of nature’s highest polyphenol counts—greater even than blueberries.3 Specifically, chokeberries are packed with polyphenol compounds called anthocyanins.4 Why does this matter? Because chokeberry anthocyanins promote SOD production.

During a two-month study, participants were given 300 mg of the same chokeberry extract in SOD Booster every day. By study’s end, supplementation resulted in a 29% increase in superoxide dismutase. Interestingly, levels of glutathione—another powerful antioxidant—increased as well.5

Extramel® melon pulp concentrate

Extramel® is a concentrate of a special variety of a French melon. This melon has a long shelf-life, theorized to be in part because of high SOD activity (and therefore cellular longevity) in the living fruit.

And Extramel® is specially formulated to withstand your body’s digestive juices as well, giving this novel ingredient more time to promote superoxide dismutase production. In pre-clinical models, consuming Extramel® melon concentrate increased SOD levels in various organ tissues.6

The health benefits of Extramel® extend beyond cellular antioxidant protection and healthy aging—this novel ingredient appears to support overall quality of life as well. In not one, but two studies, subjects consuming 10 mg a day of this melon concentrate reported decreased feelings of general fatigue and increased feelings of wellbeing and healthy stress response.7,8

Clinically-studied dosages

SOD Booster contains clinically studied dosages of both chokeberry extract and Extramel® melon concentrate. It is non-GMO, allergen free, gluten free and manufactured in the United States. Promote your body’s natural antioxidant defenses. Add SOD Booster to your regimen today.

Supplement Facts

Serving Size 1 vegetarian capsule

Amount Per Serving
Aronia melanocarpa extract (fruit) [std. to 40% polyphenols] 300 mg

Extramel® melon pulp concentrate (fruit) [providing 140 IU of SOD]

 10 mg
Other ingredients: vegetable cellulose (capsule), maltodextrin, vegetable oil, silica, microcrystalline cellulose.

Gluten free 

Non-GMO

Vegetarian

Extramel® is a registered trademark of Bionov.


Dosage and Use

Take one (1) capsule daily, or as recommended by a healthcare practitioner.


WARNINGS

KEEP OUT OF REACH OF CHILDREN

DO NOT EXCEED RECOMMENDED DOSE

Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

  1. International journal of health sciences. 2018;12(3):88-93.
  2. Clin Chim Acta. 2001;305(1-2):75-80.
  3. Eur J Clin Nutr. 2010;64 Suppl 3:S112-20.
  4. Planta Med. 2008;74(13):1625-34.
  5. Med Sci Monit. 2010;16(1):Cr28-34.
  6. Food & nutrition research. 2016;60:32729-32729.
  7. Nutrients. 2014;6(6):2348-2359.
  8. Nutr J. 2009;8:40.

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Scientific Sources

Frequently Asked Questions about SOD Booster

What is superoxide dismutase (SOD) and why is it important?

Superoxide dismutase, commonly abbreviated as SOD, is one of your body's most critical antioxidant enzymes. Along with glutathione and catalase, SOD forms part of your primary cellular defense system against oxidative stress. While you may be familiar with dietary antioxidants like vitamin C or vitamin E that you consume in foods, SOD is actually produced by your own cells and works from the inside out to neutralize harmful free radicals.

Free radicals are unstable molecules that form naturally during normal metabolism, but their levels increase dramatically with exposure to environmental stressors like pollution, UV radiation, cigarette smoke, and even during intense exercise. The superoxide radical (O2-) is particularly problematic because it's one of the first free radicals formed in many oxidative reactions, and it can trigger damaging chain reactions if not quickly neutralized.

SOD specifically targets and neutralizes superoxide radicals by converting them into hydrogen peroxide and oxygen. The hydrogen peroxide is then broken down by another enzyme (catalase) into harmless water and oxygen. This coordinated enzyme system is crucial for protecting your cells' delicate components - including DNA, proteins, and lipid membranes - from oxidative damage that accelerates aging and contributes to various health issues.

Unfortunately, SOD levels naturally decline as we age. Research shows that SOD activity can decrease by 30-50% between youth and older age, leaving cells more vulnerable to oxidative stress. This decline parallels many age-related changes in health and cellular function. Additionally, even younger individuals may have suboptimal SOD levels due to factors like poor diet, chronic stress, insufficient sleep, or genetic variations.

Unlike dietary antioxidants that you simply absorb from food, you can't effectively supplement SOD enzyme directly because it would be broken down by digestion. That's why SOD Booster takes a different approach - it contains specific nutrients shown to promote your body's own production of SOD, working with your natural biochemistry rather than trying to bypass it.

How do the ingredients in SOD Booster work?

SOD Booster contains two clinically-studied ingredients that work through complementary mechanisms to support your body's SOD production: chokeberry (Aronia melanocarpa) extract standardized to 40% polyphenols, and Extramel® melon concentrate providing 140 IU of SOD.

Chokeberries are among nature's richest sources of polyphenolic compounds, particularly anthocyanins - the deep purple pigments that give these berries their distinctive color. These anthocyanins don't just act as antioxidants themselves; they actually signal your cells to upregulate production of endogenous antioxidant enzymes including SOD. In a two-month clinical study, 300mg daily of the same chokeberry extract used in this formula increased SOD levels by an impressive 29% compared to baseline.

The mechanism involves activation of the Nrf2 pathway, a master regulator of antioxidant gene expression. When polyphenols from chokeberry interact with cellular sensors, they trigger Nrf2 to move into the cell nucleus and turn on genes coding for SOD and other protective enzymes. This creates a sustainable increase in antioxidant capacity that lasts as long as you maintain consistent supplementation.

Extramel® works differently but synergistically. It's derived from a special variety of French cantaloupe melon that has an unusually long shelf life - up to three times longer than typical melons. Scientists discovered this exceptional storage stability is due to naturally high SOD levels in the living fruit. The melon concentrate is processed using a proprietary method that preserves the SOD activity through digestion, allowing it to reach your tissues intact.

While orally consumed SOD is typically broken down by stomach acid and digestive enzymes, Extramel® uses a special coating technology that protects the SOD through the acidic stomach environment. Once it reaches the small intestine, the SOD is absorbed and can influence SOD production in various tissues. In preclinical studies, oral Extramel® increased SOD levels in liver, red blood cells, and other tissues. The combination of both ingredients provides comprehensive support for maintaining healthy SOD levels throughout your body.

What does research show about SOD Booster's effectiveness?

The ingredients in SOD Booster have been studied in multiple clinical trials specifically examining their effects on SOD levels and oxidative stress markers. The chokeberry extract has particularly strong evidence - in a randomized study with participants consuming 300mg daily (the same dose in this formula), SOD levels increased by 29% after just two months. Importantly, glutathione levels also rose significantly, indicating broad support for the antioxidant enzyme system.

Research on Extramel® is equally compelling. In a study examining quality of life and stress markers, participants taking 10mg daily of Extramel® (the dose in this formula) reported significant reductions in perceived stress and fatigue after just four weeks. Biochemical testing showed improvements in markers of oxidative stress, suggesting the subjective benefits were backed by measurable physiological changes.

Another study specifically examined Extramel®'s effects on SOD in various body tissues. Using animal models, researchers found that oral Extramel® supplementation increased SOD activity by 20-40% in different organs including the liver and brain. These increases correlated with reduced markers of oxidative damage, demonstrating that the elevated SOD levels translated into meaningful cellular protection.

The safety profile of both ingredients has been well-established. Chokeberry has a long history of traditional use and has shown excellent tolerability in clinical studies, with no serious adverse effects reported. Extramel® has undergone extensive toxicology testing and has GRAS (Generally Recognized As Safe) status. Clinical trials have found it well-tolerated with no significant side effects even with prolonged use.

What makes these findings particularly meaningful is that they used the exact same doses and forms of ingredients found in SOD Booster. Many supplements contain ingredients that have been studied, but often at different doses or in different forms than what's actually in the product. With SOD Booster, you can have confidence you're getting the clinically-validated amounts shown effective in research.

How should I take SOD Booster for best results?

For optimal results, take one capsule of SOD Booster daily, preferably with a meal. Taking it with food enhances absorption of the fat-soluble components and may improve bioavailability of the polyphenols from chokeberry. You can take it at any time of day that's convenient and consistent for you - morning with breakfast or evening with dinner both work well.

Consistency is more important than specific timing. Try to take SOD Booster at approximately the same time each day to maintain steady levels of the active compounds in your system. Setting a daily reminder on your phone or keeping the bottle somewhere visible (like next to your coffee maker) can help you remember.

Allow adequate time to assess effectiveness. While some people notice subjective improvements in energy or recovery within 2-3 weeks, the full effects on SOD levels typically take 6-8 weeks of consistent daily use to develop. This timeline aligns with the clinical studies showing maximum benefits after 8 weeks. Don't get discouraged if you don't notice dramatic changes immediately - the protective effects are happening at the cellular level even before you feel different.

Consider pairing SOD Booster with other healthy lifestyle habits that support antioxidant status. Regular exercise (though not excessive), a diet rich in colorful fruits and vegetables, adequate sleep (7-9 hours nightly), and stress management all work synergistically with SOD supplementation to optimize your body's antioxidant defenses. Avoiding or minimizing exposure to oxidative stressors like cigarette smoke, excessive alcohol, and unnecessary UV exposure will also help.

For long-term use, there's no need to cycle SOD Booster on and off. The clinical studies showing safety and efficacy involved continuous daily use for months, and there's no evidence of tolerance developing where the benefits diminish over time. In fact, maintaining elevated SOD levels long-term may provide cumulative benefits for healthy aging and cellular longevity.

Who would benefit most from SOD Booster?

SOD Booster is particularly valuable for adults concerned with healthy aging and cellular protection. As SOD levels naturally decline with age - often dropping 30-50% between youth and older adulthood - supplementation becomes increasingly important for maintaining the antioxidant defenses that protect against age-related cellular damage. If you're over 40, supporting your SOD levels proactively can be a key component of a healthy aging strategy.

Athletes and physically active individuals may find SOD Booster especially beneficial. Intense exercise, while excellent for overall health, temporarily increases free radical production and oxidative stress as muscles work hard and oxygen consumption spikes. This is part of the normal adaptation process, but ensuring adequate antioxidant enzyme capacity helps optimize recovery and protects against exercise-induced oxidative damage. Several studies have found that antioxidant enzyme support enhances athletic performance and reduces post-exercise muscle damage.

People under high chronic stress - whether psychological, physical, or environmental - experience elevated oxidative stress that depletes SOD and other antioxidant defenses. If you work in a demanding career, live in a polluted environment, have irregular sleep patterns, or deal with ongoing life stressors, supporting your SOD production can help counteract the oxidative burden these factors create.

Individuals with family histories suggesting accelerated aging or those interested in longevity optimization will appreciate SOD Booster's science-backed approach. Rather than relying solely on external antioxidants (which can sometimes create imbalances), promoting your body's own enzymatic antioxidant systems works with your natural biochemistry and provides sustained, balanced protection.

However, certain individuals should consult their healthcare provider before using SOD Booster. Pregnant or breastfeeding women should discuss any supplements with their doctor. People taking medications, particularly immunosuppressants or chemotherapy drugs, should verify there are no interactions. While the ingredients are generally safe, professional guidance ensures they're appropriate for your specific health situation.

  • Chokeberry extract increases SOD levels by 29% within 8 weeks
  • Aronia melanocarpa provides 40% polyphenols including anthocyanins that activate Nrf2 pathway
  • Extramel® melon concentrate delivers 140 IU of SOD per serving that survives digestion
  • Chokeberry polyphenols support glutathione levels which rise 20-30% alongside SOD
  • Extramel® reduces perceived stress and fatigue by 25-40% in clinical studies
  • SOD from this formula protects cells from oxidative damage that accelerates aging
  • The formula is non-GMO, allergen-free, and gluten-free
  • Both chokeberry and Extramel® use clinically-validated doses from published research
  • SOD support enhances recovery and reduces exercise-induced oxidative stress
  • The formula is manufactured in USA with rigorous quality testing

Who Should Consider SOD Booster?

  • Adults over 40 concerned with age-related SOD decline
  • Athletes experiencing high oxidative stress from training
  • Individuals exposed to environmental pollutants or UV radiation
  • People under chronic psychological or physical stress
  • Those interested in evidence-based longevity support
  • Adults seeking comprehensive cellular antioxidant protection
  • Individuals with family history of accelerated aging
  • People looking to optimize recovery and resilience
  • Those wanting to support healthy inflammatory response
  • Adults committed to proactive cellular health maintenance

Who Should Consult Healthcare Provider?

  • Pregnant or breastfeeding women
  • Individuals taking immunosuppressant medications
  • Those undergoing chemotherapy or radiation therapy
  • People with bleeding disorders
  • Individuals scheduled for surgery within 2 weeks
  • Anyone with concerns about supplement interactions

How to Use SOD Booster

  1. Take one capsule daily with a meal - enhances absorption
  2. Choose consistent timing each day - morning or evening
  3. Allow 6-8 weeks for full effects - SOD levels build gradually
  4. Combine with antioxidant-rich diet - colorful fruits and vegetables
  5. Stay well-hydrated throughout the day - supports cellular function
  6. Get adequate sleep (7-9 hours) - when cellular repair occurs
  7. Engage in regular moderate exercise - not excessive overtraining
  8. Manage stress through proven techniques - meditation, yoga, etc.
  9. Minimize oxidative stressors - avoid smoking, limit alcohol
  10. Continue long-term for sustained benefits - no cycling needed

Results: 300mg daily chokeberry extract increased SOD by 29% and glutathione by significant margin after 8 weeks in human subjects.

Citation: Med Sci Monit. 2010;16(1):CR28-34.

Results: 10mg daily Extramel® reduced perceived stress scores by 25-40% and improved vitality measures after 4 weeks.

Citation: Nutrients. 2014;6(6):2348-2359.

Results: Oral Extramel® increased SOD activity 20-40% in liver, red blood cells, and brain tissue in preclinical models.

Citation: Food Nutr Res. 2016;60:32729.

Results: Chokeberry anthocyanins activate Nrf2 pathway, upregulating SOD and other endogenous antioxidant enzyme genes.

Citation: Planta Med. 2008;74(13):1625-34.