PQQ Pyrroloquinoline quinone

Category: Mitochondria and energy

Manufacturer:

More than just an antioxidant

  • Supports mitochondrial biogenesis
  • Improves cognitive health and memory
  • Anti-inflammation and antioxidation effects
  • Supports Cardiovascular health
  • High content of active ingredient in one capsule
  • Raw material produced in Japan using a unique fermentation and purification process
  • Product is suitable for vegetarians due to Vcaps® capsule

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PQQ Pyrroloquinoline quinone

60 capsules

Item Catalog Number: K1724EN

Original product name: PQQ Pirolochinolinochinon

PQQ is definitely more than just a strong antioxidant. This nutrient is found in fruits, vegetables and breast milk but only bacteria can produce it.

PQQ - Pyrroloquinoline quinone is a vitamin-like micronutrient wchich belongs to the quinone cofactors family. As an enzymatic cofactor, PQQ transfers electrons, which is a key for the proper functions of mitochondria, which are a kind of "cellular power plants". PQQ helps reverse mitochondrial disorders and stimulates the growth of new mitochondria.

Researchers have found that PQQ regulates the activity of lactate dehydrogenase enzyme which participate in the process of energy production in many organs and tissues throughout the human body.[7]

PQQ affects biological processes such as mitochondriogenesis, reproduction, growth and aging.

As it was shown, in an early stage of development PQQ deficiency reduces mitochondria content and mitochondrial-related gene expression. Current observations suggest that PQQ has strong potential as a potent therapeutic nutraceutical.[1,2]

One of study[3] showed, that daily supplementation with 20 mg PQQ optimizes mitochondrial biogenesis in human subjects.[1-3] Moreover, PQQ supplementation (10–20 mg per day) improved cognitive function and memory in human subjects [1,2,4-6].

Benefits at a Glance:

  • Anti-inflammation and antioxidation effects
  • Supports mitochondrial biogenesis
  • Improves cognitive health and memorySupports Cardiovascular health
  • High content of active ingredient in one capsule
  • Raw material produced in Japan using a unique fermentation and purification process
  • Product is suitable for vegetarians due to Vcaps® capsule

PQQ shows anti-inflammation and antioxidation effects. PQQ protects the circulatory system, especially the heart, against the destructive effects of free radicals. It also supports proper blood flow in the heart muscle.[8,9]

Supplement Facts

Daily dose: 1 capsule

Amount Per Day (1 capsule)

PQQ (pyrroloquinoline quinone disodium salt)

20 mg

Ingredients: bulking agent: microcrystalline cellulose; pyrroloquinoline quinone disodium salt (PQQ); capsule shell: hydroxypropylmethylcellulose.


Vcaps® is a trademark of Lonza or its affiliates.

Active ingredient supplier: Mitsubishi Gas Chemical Company, Inc. Japan

Dosage and Use

Take one (1) capsule daily or as recommended by a healthcare practitioner.

Warnings:

Before you start using any dietary supplement, consult your doctor. 

Dietary supplements are not medicines.

Do not exceed the recommended daily dose.

Dietary supplements cannot be used as a substitute for a varied diet.

Do not use in case of hypersensitivity to any ingredient of the preparation.

The product should not be used by pregnant or breastfeeding women and children and adolescents under 18 years of age.

  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533503/
  2. Karen R. Jonscher, Winyoo Chowanadisai, Robert B. Rucker "Pyrroloquinoline-Quinone Is More Than an Antioxidant: A Vitamin-like Accessory Factor Important in Health and Disease Prevention"
  3. Hwang P.S., Machek S.B., Cardaci T.D., Wilburn D., Kim C.S., Suezaki E.S., Willoughby D.S. Effects of pyrroloquinoline quinone (PQQ) supplementation on aerobic exercise performance and indices of mitochondrial biogenesis in untrained men. J. Am. Coll. Nutr. 2019;39:547–556. doi: 10.1080/07315724.2019.1705203.
  4. Wen H., He Y., Zhang K., Yang X., Hao D., Jiang Y., He B. Mini-review: Functions and action mechanisms of PQQ in osteoporosis and neuro injury. Curr. Stem Cell Res. Ther. 2020;15:32–36. doi: 10.2174/1574888X14666181210165539.
  5. Shiojima Y., Takahashi M., Takahashi R., Moriyama H., Bagchi D., Bagchi M., Akanuma M. Effect of dietary pyrroloquinoline quinone disodium salt on cognitive function in healthy volunteers: A randomized, double-blind, placebo-controlled, parallel-group study. J. Am. Coll. Nutr. 2021;20:1–14. doi: 10.1080/07315724.2021.1962770.
  6. Nakano M., Murayama Y., Hu L., Ikemoto K., Uetake T., Sakatani K. Effects of antioxidant supplements (BioPQQ™) on cerebral blood flow and oxygen metabolism in the prefrontal cortex. Adv. Exp. Med. Biol. 2016;923:215–222. doi: 10.1007/978-3-319-38810-6_29.
  7. https://chemistry.berkeley.edu/news/behind-scenes-look-longevity-vitamin-pqq
  8. Cardiovasc Drugs Ther. 2004 Nov;18(6):421-31.
  9. Cardiovasc Pharmacol Ther. 2006 Jun;11(2):119-28.

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