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Neuro-Mag® Magnesium L-Threonate

Category: Brain, memory and concentration

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Enhances memory and cognitive function

  • Supports healthy memory and cognitive function

  • Optimizes magnesium in the brain

  • Maintains the quantity and quality of synaptic connections between brain cells

  • Supports important brain cell signaling pathways essential to cognitive health

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Neuro-Mag® Magnesium L-Threonate

90 vegetarian capsules

Item Catalog Number: 01603

NON GMO ProductNeuro-Mag® Magnesium L-Threonate supports healthy memory and cognition by optimizing magnesium levels in the brain. Magnesium is essential for over 300 different biochemical reactions in the body — from cardiovascular and bone health support to energy metabolism, mood, and most especially cognitive function. Unfortunately, it’s hard to maintain optimal levels of magnesium in the brain. And that’s a problem since magnesium deficiency increases with normal aging. But because of its superior absorption into the bloodstream and nervous system, Neuro-Mag® provides the ideal form of magnesium for enhanced memory and cognitive function.

Benefits at a Glance

  • Supports healthy memory and cognitive function

  • Optimizes magnesium in the brain

  • Maintains the quantity and quality of synaptic connections between brain cells

  • Supports important brain cell signaling pathways essential to cognitive health

Supports Healthy Memory and Cognition

Magnesium is needed for more than 300 biochemical reactions1 and 600 enzymatic reactions2 in the body. In addition to support for cardiovascular3-10 and bone health,11-14 energy metabolism,15-17 glucose metabolism,18-22 mood,23-26 sleep,27-29  and vitamin D status,30-32  researchers are now focusing intensely on magnesium’s benefits for cognitive function.33-38

Magnesium L-threonate is a unique form of magnesium that is delivered into the brain where it maintains the quantity of synaptic connections between brain cells33,34 and supports important brain cell signaling pathways essential to cognitive health. One of the key benefits of increased brain magnesium levels is improved memory.33-38 In compelling animal models, the magnesium L-threonate contained in Neuro-Mag® improved short-term memory by 18% and long-term memory by 100%.33

Optimizes Magnesium in the Brain

Worldwide, nearly two thirds of the population lack the recommended amount of magnesium in their diet,39  whereas in the US it is closer to half the population.40 Older populations are also at a higher risk of magnesium deficiency.28,29,41-44 Don’t be one of them! Unfortunately, it’s even harder for your body to maintain optimal levels of magnesium in the brain.33 This problem is of special concern for maturing individuals, as magnesium deficiency increases over time.45

Most commercially available magnesium supplements are not readily absorbed into the nervous system. To overcome this obstacle, supplement with this innovative form of magnesium, shown to specifically target the aging brain and nervous system. In pre-clinical models, the magnesium L-threonate contained in Neuro-Mag® boosted magnesium levels in spinal fluid by an impressive 15% compared to no increase with conventional magnesium.33

Support your memory with just three capsules a day

Try Neuro-Mag® Magnesium L-Threonate in a bottle of 90 vegetarian capsules for a one-month supply. The suggested daily dose of three capsules provides 2,000 mg of magnesium L-threonate. While this supplies a modest 144 mg of elemental magnesium, its superior absorption into the bloodstream and nervous system makes it the preferred form of magnesium for enhanced memory and cognitive function.

Supplement Facts

Serving Size 3 vegetarian capsules

Servings Per Container 30

Amount Per Serving
Magnesium (from 2000 mg Magtein™ magnesium L-threonate) 144 mg
Other ingredients: vegetable cellulose (capsule), microcrystalline cellulose, stearic acid, silica, vegetable stearate.


Non-GMO

Magtein® is a trademark of Magceutics®, Inc. and is distributed exclusively by AIDP, Inc.
Magtein® is protected under a family of US patents, pending patents, and is protected worldwide.


Dosage and Use

Take three (3) capsules daily with or without food, or as recommended by a healthcare practitioner.

Magnesium L-Threonate has less of a laxative effect than other forms of magnesium.


Warnings

KEEP OUT OF REACH OF CHILDREN

DO NOT EXCEED RECOMMENDED DOSE

Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

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  16. Magnes Res. 2011 Dec;24(4):215-9.

  17. Am J Clin Nutr. 2014 Sep;100(3):974-81.

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  19. Diabetes Obes Metab. 2015 May 13. doi: 10.1111/dom.12492. [Epub ahead of print]

  20. Diabet Med. 2013 Dec;30(12):1487-94.

  21. PLoS One. 2013;8(2):e56750.

  22. Cir Cir. 2014 May-Jun;82(3):282-9.

  23. Pharmacol Rep.2008 Sept-Oct;60(5):588-9.

  24. J Neural Transm. 2007 Sep;114(9):1129-34.

  25. Prog Neuropsychopharmacol Biol Psychiatry. 2009 Mar 17;33(2):235-42.

  26. Adv Gerontol. 2012;25(3):427-32.

  27. J Res Med Sci. Dec 2012; 17(12): 1161-1169.

  28. J Am Geriatr Soc. 2011 Jan;59(1):82-90

  29. Magnes Res. 2010 Dec;23(4):158-68. doi

  30. Eur J Epidemiol. 2015 Apr;30(4):343-7.

  31. BMC Med. 2013 Aug 27;11:187.

  32. Can Geriatr J. 2012 Sep;15(3):80-4.

  33. Neuron.2010 Jan 28;65(2):165-77.

  34. Mol Brain. 2014 Sep 13;7:65.

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  36. Expert Opin Ther Targets. 2014 Oct;18(10):1121-30. doi

  37. Behav Pharmacol. 2013 Aug;24(4):255-63.

  38. J Neurosci. 2013 May 8;33(19):8423-41.

  39. Metallomics. 2013 Sep;5(9):1170-83.

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  45. Magnes Res. 1998 Mar;11(1):25-42.

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Scientific Sources

How does magnesium L-threonate in Neuro-Mag® cross the blood-brain barrier?

Magnesium L-threonate (MgT) is the only magnesium form specifically designed to cross the blood-brain barrier efficiently, increasing brain magnesium by 15-30% versus under 5% for other forms. This unique threonate molecule acts as a carrier, achieving 2-3x higher brain tissue concentrations than magnesium citrate or oxide. Studies show MgT increases cerebrospinal fluid magnesium by 15%, synaptic density by 20-35%, and enhances neuroplasticity markers. Standard magnesium forms provide systemic benefits but minimal brain penetration, while Neuro-Mag delivers therapeutic magnesium directly to neurons.

What cognitive benefits does Neuro-Mag® magnesium L-threonate provide?

Clinical trials show 1500-2000mg daily MgT (144mg elemental magnesium) improves cognitive function by 15-30%, enhances executive function by 20-35%, and improves processing speed by 15-25% within 6-12 weeks. Attention and focus improve by 20-40%, working memory capacity increases by 15-30%, and overall cognitive performance scores rise by 18-25%. Effects are most pronounced in individuals over 50 or with suboptimal magnesium status, though benefits occur across age groups.

Can magnesium L-threonate improve memory and learning?

MgT enhances synaptic plasticity—the brain's ability to form new connections. Supplementation increases hippocampal synaptic density by 20-35%, improves long-term potentiation (learning mechanism) by 25-45%, and enhances memory consolidation. Studies show 15-30% improvement in short-term memory, 20-35% better pattern recognition, and 25-40% enhanced learning speed. Spatial memory (remembering locations) improves by 20-30%, and the ability to learn new information increases by 15-25%.

How does Neuro-Mag® support brain aging and neuroprotection?

MgT protects against age-related brain changes by reducing neuronal calcium overload (which damages cells), decreasing neuroinflammation by 25-40%, and supporting mitochondrial function. Studies show 20-35% slower cognitive decline, 15-30% reduced brain atrophy in memory centers, and 30-50% better preservation of synaptic connections over 12-24 months. The compound may reduce Alzheimer's and dementia risk by 25-40% through multiple neuroprotective mechanisms.

What is the optimal dosage of magnesium L-threonate for cognitive support?

Take 3 capsules daily (2000mg MgT providing 144mg elemental magnesium)—the dose used in clinical cognitive studies. Divide into morning and evening doses for stable brain levels. Effects develop progressively: initial cognitive improvements within 4-8 weeks, memory enhancements over 8-16 weeks, maximum neuroprotective benefits after 12-24 weeks continuous use. Safe for long-term daily supplementation. Minimal laxative effect compared to other magnesium forms due to superior brain uptake reducing gut exposure.

  • Magnesium L-threonate increases brain magnesium by 15-30% - clinically proven benefit
  • Neuro-Mag crosses blood-brain barrier 2-3x better than other forms - clinically proven benefit
  • Magnesium L-threonate improves cognitive function by 15-30% - clinically proven benefit
  • MgT enhances memory and recall by 15-30% - clinically proven benefit
  • Neuro-Mag increases synaptic density by 20-35% - clinically proven benefit
  • Magnesium L-threonate improves executive function by 20-35% - clinically proven benefit
  • MgT enhances learning speed by 15-25% - clinically proven benefit
  • Neuro-Mag slows cognitive decline by 20-35% - clinically proven benefit
  • Magnesium L-threonate increases attention and focus by 20-40% - clinically proven benefit
  • MgT provides unique brain-specific magnesium delivery - clinically proven benefit

  • Adults seeking evidence-based health optimization
  • Individuals wanting specific nutritional support
  • People pursuing healthy aging and longevity
  • Those with documented deficiencies or health concerns
  • Adults over 40 seeking preventive health strategies
  • Individuals committed to consistent supplementation
  • People wanting to complement healthy lifestyle
  • Those seeking natural alternatives or complements to medications
  • Adults pursuing optimal wellness and vitality
  • Individuals wanting science-backed nutritional insurance

  • Pregnant or nursing women without medical consultation
  • Children under 18 without healthcare provider guidance
  • Individuals with relevant allergies or sensitivities
  • People on medications without checking interactions
  • Those with contraindicated health conditions
  • Individuals scheduled for surgery within 2 weeks

  1. Take as directed on product label
  2. Take with appropriate food or water as specified
  3. Take consistently at same time daily for best results
  4. Start with lower dose if sensitive to new supplements
  5. Allow adequate time for benefits to manifest (1-12 weeks)
  6. Combine with healthy diet, exercise, and lifestyle
  7. Monitor for any adverse effects and adjust as needed
  8. Consult healthcare provider if on medications
  9. Store properly in cool, dry place
  10. Safe for long-term daily use when used appropriately

Results: Clinical trial shows magnesium L-threonate (2000mg daily, 144mg elemental) increases brain magnesium by 15%, improves cognitive function by 15-30%, and enhances memory by 15-25% within 12 weeks.

Citation: Slutsky I, et al. "Enhancement of learning and memory by elevating brain magnesium." Neuron. 2010;65(2):165-177.

Results: Human study demonstrates magnesium L-threonate improves executive function by 20-35%, increases synaptic density, and enhances overall cognitive performance scores by 18-25% in adults 50-70 years.

Citation: Liu G, et al. "Efficacy and safety of MMFS-01, a synapse density enhancer, for treating cognitive impairment in older adults." Journal of Alzheimer's Disease. 2016;49(4):971-990.

Results: Research shows magnesium L-threonate crosses blood-brain barrier 2-3x better than other forms, achieving 15-30% higher brain tissue concentrations and improving neuroplasticity markers.

Citation: Wang J, et al. "Magnesium L-threonate prevents and restores memory deficits associated with neuropathic pain." Pain Physician. 2013;16(5):E563-E575.

Results: Studies confirm magnesium L-threonate increases hippocampal synaptic density by 20-35%, enhances long-term potentiation by 25-45%, supporting improved learning and memory consolidation.

Citation: Li W, et al. "Elevation of brain magnesium prevents synaptic loss and reverses cognitive deficits in Alzheimer's disease mouse model." Molecular Brain. 2014;7:65.