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Pycnogenol® EU

Category: Anti-aging

Manufacturer:

Unique anti-aging extract for health and vascular support

  • Supports the body’s defenses against 5 mechanisms of premature aging

  • Patented and standardized natural botanical extract

  • Forty years of clinical testing

  • Supports healthy cell membrane and DNA function

  • Modulates inflammatory factors through normal mechanisms

  • Supports healthy antioxidant function and cell metabolism

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Pycnogenol®

100 mg, 60 vegetarian capsules

Item Catalog Number: 01637EU

NON GMO ProductPycnogenol® French Maritime Pine Bark Extract is a time-tested anti-aging solution. This natural plant extract contains procyanidins, bioflavonoids, and other beneficial molecules that help the body fight five processes associated with premature aging. Forty years of studies on Pycnogenol® have helped validate its powerful anti-aging properties.

Benefits at a Glance

  • Supports the body’s defenses against 5 mechanisms of premature aging

  • Patented and standardized natural botanical extract

  • Forty years of clinical testing

  • Supports healthy cell membrane and DNA function

  • Modulates inflammatory factors through normal mechanisms

  • Supports healthy antioxidant function and cell metabolism

Comprehensive Anti-Aging Power

The constituents in Pycnogenol® have a synergistic effect against factors associated with premature aging, working together to:

  • Promote the integrity and normal characteristics of cell membranes.1-4

  • Support healthy DNA function through enhanced antioxidant activity and other potential mechanisms.5-8

  • Promote a healthy inflammatory response through normal modulation of cytokine molecules.9-12

  • Fight oxidative stress by encouraging healthy and normal function of antioxidant systems that help inhibit free radical activity and protect DNA.13-17

  • Encourage healthy cellular metabolism of sugar, healthy blood sugar levels, normal absorption of sugar in the intestine, and post-meal blood sugar levels already within the normal range.18-26

This is truly a one-stop formula that can help you beat Father Time at his own game. Add Pycnogenol® to your anti-aging regimen today.

Supplement Facts

Serving Size 1 vegetarian capsule

Amount per day (2 capsules)
Pycnogenol® dried French Maritime pine extract (bark) [std. to 65% procyanidins] 200 mg
Ingredients: Bulking agent (microcrystalline cellulose/cellulose gel), maritime pine bark extract (Pinus pinaster Aiton), capsule (hydroxypropyl methyl cellulose), anti-caking agents (fatty acids, silicon dioxide [nano])


Non-GMO

Pycnogenol® is a registered trademark of Horphag Research Ltd. Use of this product may be protected by one or more U.S. patents and other international patents. Supported by over 40 years of research.


Dosage and Use


Take one (1) capsule once or twice daily, with or without food, or as recommended by a healthcare practitioner.


Warnings

KEEP OUT OF REACH OF CHILDREN

DO NOT EXCEED RECOMMENDED DOSE

Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.


  1. Gen Physiol Biophys. 2004 Mar;23(1):39-51.

  2. Phytother Res. 2008 Mar;22(3):384-8.

  3. Biol Pharm Bull. 2000 Jun;23(6):735-7.

  4. Phytother Res. 2004 Mar;18(3):244-6.

  5. Fitoterapia. 2010 Oct;81(7):724-36.

  6. Drug Dev Ind Pharm. 1998 Feb;24(2):139-44.

  7. Free Radic Res. 2006 Sep;40(9):1003-10.

  8. Phytother Res. 2005 Mar;19(3):262.

  9. Photochem Photobiol. 2004 Feb;79(2):193-8.

  10. Free Radic Biol Med. 2012 Feb 15;52(4):765-74.

  11. J Inflamm (Lond). 2006 Jan 27;3:1.

  12. Food Chem Toxicol. 2011 Sep;49(9):2196-201.

  13. Int J Clin Pharmacol Ther. 2002 Apr;40(4):158-68.

  14. Redox Rep. 2006;11(4):163-72.

  15. J Psychopharmacol. 2008 Jul;22(5):553-62.

  16. Redox Rep. 2008;13(6):271-6.

  17. Lipids. 2002 Oct;37(10):931-4.

  18. Diabetes Care. 2004 Mar;27(3):839.

  19. Res Pharm Sci. 2011 Jan;6(1):1-11.

  20. Chinese Pharmacological Bulletin, 2003; 19(4):437-440.

  21. Nutr Res. 2008 May;28(5):315-20.

  22. Phytother Res. 2010 Aug;24(8):1242-9.

  23. Life Sci. 2004 Oct 8;75(21):2505-13.

  24. Chem Biol Interact. 2010 Jul 30;186(2):219-27.

  25. Phytother Res. 2013 Oct;27(10):1572-8.

  26. Phytother Res. 2015 Jul;29(7):949-68.

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Scientific Sources

What is Pycnogenol and what makes it a powerful antioxidant?

Pycnogenol is a standardized extract from French maritime pine bark containing powerful polyphenolic antioxidants including proanthocyanidins, bioflavonoids, and organic acids. This unique combination provides antioxidant activity up to 50 times more powerful than vitamins C and E in certain tests. Pycnogenol's molecular structure allows it to cross the blood-brain barrier and protect neurological tissues. The extract has been extensively researched with over 400 published studies demonstrating its benefits for cardiovascular health, circulation, skin health, cognitive function, and more. Pycnogenol's standardization ensures consistent potency and reliable effects, making it one of the most well-documented natural antioxidants available.

How does Pycnogenol support cardiovascular and circulatory health?

Pycnogenol supports cardiovascular health through multiple mechanisms. It enhances endothelial function by supporting nitric oxide production, which helps blood vessels relax and maintain healthy blood flow. The extract protects LDL cholesterol from oxidation, reducing formation of oxidized cholesterol that contributes to arterial plaque. Pycnogenol supports healthy platelet function without excessive clotting. It strengthens capillary walls, reducing permeability and supporting microcirculation throughout the body. Clinical studies show Pycnogenol helps maintain healthy blood pressure already within normal range. The extract also reduces swelling and supports comfortable leg circulation, making it beneficial for those experiencing occasional leg heaviness or discomfort from prolonged sitting or standing.

What skin health benefits does Pycnogenol provide?

Pycnogenol offers impressive skin health benefits through both antioxidant protection and collagen support. It protects skin from UV damage by neutralizing free radicals generated by sun exposure and reducing inflammatory responses to UV radiation. Pycnogenol binds to collagen and elastin proteins in skin, protecting them from enzymatic degradation and oxidative damage. Clinical studies show Pycnogenol supplementation improves skin hydration, elasticity, and smoothness while reducing fine lines and wrinkles. The extract supports healthy skin pigmentation and may reduce appearance of age spots. By supporting microcirculation, Pycnogenol enhances nutrient and oxygen delivery to skin cells, promoting healthy skin appearance and natural radiance from within.

Can Pycnogenol support cognitive function and brain health?

Yes, Pycnogenol crosses the blood-brain barrier and provides direct neuroprotection. Its antioxidant properties protect brain cells from oxidative stress and inflammation associated with cognitive decline. By supporting cerebral circulation, Pycnogenol enhances oxygen and nutrient delivery to brain tissue. Studies show Pycnogenol supplementation improves attention, memory, and cognitive performance, particularly in individuals experiencing age-related cognitive changes. The extract may support healthy neurotransmitter function and protect against excitotoxicity. Research indicates Pycnogenol reduces oxidative stress biomarkers in the brain while supporting mitochondrial function in neurons. These neuroprotective effects make Pycnogenol valuable for maintaining cognitive function and supporting brain health throughout aging.

How should I take Pycnogenol for optimal health benefits?

For general health maintenance and antioxidant protection, typical doses range from 50-150 mg daily. Take Pycnogenol with meals to enhance absorption, though it can be taken with or without food. For specific health concerns like circulation support or skin health, higher doses (100-200 mg daily) may be recommended. Divide larger doses between morning and evening for more stable blood levels. Benefits develop gradually—allow 4-8 weeks of consistent supplementation to experience noticeable improvements in circulation, skin, or cognitive function. Pycnogenol has excellent safety with no serious adverse effects reported in clinical studies. Continue long-term use for sustained benefits as Pycnogenol provides ongoing antioxidant and vascular protection.

  • Pycnogenol provides powerful antioxidant protection up to 50 times stronger than vitamins C and E - superior antioxidant
  • Supports cardiovascular health with Pycnogenol and healthy blood vessel function - heart support
  • Pycnogenol enhances circulation and microcirculation throughout entire body - circulation support
  • Protects skin from UV damage with Pycnogenol and supports collagen and elastin - skin health
  • Pycnogenol improves skin hydration elasticity and reduces fine lines and wrinkles - anti-aging
  • Supports cognitive function with Pycnogenol crossing blood-brain barrier for neuroprotection - brain support
  • Pycnogenol helps maintain healthy blood pressure already within normal range - blood pressure
  • Supports comfortable leg circulation with Pycnogenol reducing occasional swelling and heaviness - leg health
  • Standardized French maritime pine bark extract with Pycnogenol for consistent potency - quality assurance
  • Backed by over 400 published studies demonstrating Pycnogenol effectiveness and safety - research proven

  • Individuals seeking powerful antioxidant protection and comprehensive cardiovascular health support
  • People wanting to support healthy circulation and comfortable leg function from prolonged sitting
  • Those interested in protecting skin from UV damage and supporting youthful skin appearance
  • Adults concerned about cognitive function and wanting to support brain health with aging
  • Anyone seeking well-researched natural antioxidant with multiple clinically proven health benefits

  • People taking immunosuppressant medications should consult doctor before Pycnogenol use
  • Those with autoimmune conditions should seek medical guidance before supplementation
  • Pregnant or nursing women should consult healthcare provider before using Pycnogenol
  • Individuals on blood-thinning medications should verify compatibility with physician
  • People scheduled for surgery should discontinue Pycnogenol two weeks beforehand

  1. Take recommended dose typically 50-150 mg daily with meals for optimal absorption
  2. For specific health concerns higher doses 100-200 mg may be recommended by provider
  3. Divide larger doses between morning and evening for more stable blood levels
  4. Maintain consistent daily use for at least 4-8 weeks to experience benefits
  5. Can be taken with or without food though absorption may be enhanced with meals
  6. Combine with vitamin C for synergistic antioxidant protection and benefits
  7. Continue long-term use for sustained cardiovascular skin and cognitive support
  8. Store in cool dry place away from moisture to preserve extract potency

Results: Clinical trials demonstrate Pycnogenol supplementation significantly improves endothelial function and circulation, with studies showing improved flow-mediated dilation and reduced oxidative stress markers in individuals with cardiovascular concerns over 8-12 weeks.

Citation: Enseleit F, et al. Eur Heart J. 2012 Jul;33(13):1589-97.

Results: Research shows Pycnogenol protects skin from UV damage and improves skin appearance, with clinical trials demonstrating improvements in skin hydration, elasticity, and reduced pigmentation after 12 weeks of supplementation with 75-100 mg daily.

Citation: Marini A, et al. Skin Pharmacol Physiol. 2012;25(1):2-8.

Results: Studies indicate Pycnogenol supports cognitive function and attention, with controlled trials showing improvements in memory, concentration, and mental performance in students and adults experiencing age-related cognitive changes.

Citation: Ryan J, et al. J Neurosurg Sci. 2008 Sep;52(3):89-93.

Results: Clinical research demonstrates Pycnogenol reduces leg swelling and discomfort in people with venous insufficiency or prolonged immobility, with significant improvements in symptoms, leg circumference, and quality of life compared to placebo groups.

Citation: Cesarone MR, et al. Angiology. 2005 Nov-Dec;56(6):699-705.