5-LOX Inhibitor with AprèsFlex®

Category: Extracts

Manufacturer:

Promotes joint, cell & arterial health

  • Made with standardized Boswellia serrata extract
  • Promotes a healthy inflammatory response by inhibiting 5-LOX enzyme
  • Supports joint health, arterial health & healthy cell division

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21,26 €

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5-LOX Inhibitor with AprèsFlex®

100 mg, 60 vegetarian capsules

Item Catalog Number: 01639

NON GMO Product

Compounds in Boswellia extract have been shown to bind directly to 5-LOX, an enzyme that transforms fatty acids into inflammatory factors like leukotriene B4. A compound in boswellia called AKBA is the key to this beneficial action. Each 100 mg vegetarian capsule of 5-LOX Inhibitor with AprèsFlex® is standardized to provide 20% of active AKBA from boswellia.

AprèsFlex® absorbs 52% more than standard boswellia extract and is standardized for the active AKBA compound.

Benefits at a Glance:

  • Made with standardized Boswellia serrata extract
  • Promotes a healthy inflammatory response by inhibiting 5-LOX enzyme
  • Supports joint health, arterial health & healthy cell division

Better-Absorbed Boswellia

Boswellia is an extract that can inhibit inflammatory factors to support joint and arterial health. In this supplement, we use a standardized form of boswellia called AprèsFlex® that absorbs into the blood 52 percent more than previously available boswellia extracts. Each vegetarian capsule of 5-LOX Inhibitor with AprèsFlex® provides 100 mg of this innovative extract.

5-lipoxygenase (5-LOX) is an enzyme that transforms fatty acids into leukotrienes.1 Since 5-LOX levels increase over time, excess 5-LOX has been linked to some of the common effects of normal aging.2

Boswellia extract inhibits 5-LOX

The Indian plant Boswellia serrata contains compounds shown to inhibit 5-LOX to support joint and arterial health. Boswellia inhibits 5-LOX at the cellular level. Scientific data reveals that a compound in boswellia called AKBA (3-O-acetyl-11-keto-ß-boswellic acid) is the key to this beneficial action.3

But boswellia compounds are poorly absorbed into the blood. For this reason, we’ve used AprèsFlex®, a standardized form of boswellia extract. AprèsFlex® absorbs into the blood 52% more than previously available boswellia extracts.4

Dietary factors increase 5-LOX prevalence

The typical American diet adds to 5-LOX levels. Foods rich in omega-6 fatty acids like red meat, poultry, eggs and dairy products, along with high-glycemic carbohydrates, trigger production of arachidonic acid. The body produces 5-LOX enzyme in response to arachidonic acid.1

Benefits of modulating 5-LOX

5-LOX creates compounds like leukotriene B4 out of arachidonic acid. Inhibiting leukotriene B4 helps support joint, arterial and tissue health.5 Inhibiting 5-LOX also helped support healthy cell division in preclinical models.6

Each 100 mg vegetarian capsule of 5-LOX Inhibitor with AprèsFlex® is standardized to provide 20% of active AKBA from boswellia. Most people need only one capsule a day.

Supplement facts

Serving Size 1 vegetarian capsule

Amount Per Serving
AprèsFlex® (Boswellia serrata) extract (gum resin) [std. to 20% 3-O-acetyl-11-keto-ß-boswellic acid (AKBA) (20 mg)] 100 mg
Other ingredientsmicrocrystalline cellulose, vegetable cellulose (capsule), silica, vegetable stearate.

AprèsFlex® is a registered trademark of Laila Nutraceuticals exclusively licensed to PL Thomas – Laila Nutra LLC. U.S. Patent No. 8,551,496 and other patents pending.

Dosage and Use

To inhibit the 5-lipoxygenase enzyme, take one (1) capsule daily, or as recommended by a healthcare practitioner.

Warnings

KEEP OUT OF REACH OF CHILDREN

DO NOT EXCEED RECOMMENDED DOSE

Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

  1. Biochim Biophys Acta - Molecular and Cell Biology of Lipids. 2015;1851(4):331-339.
  2. Faseb j. 2000;14(10):1464-1469.
  3. Clin Pharmacokinet.2011;50(6):349-369.
  4. Mol Cell Biol.2011;354(1):189-197.
  5. Semin Immunol.2017;33:3-15.
  6. Clin Cancer Res.2005;11(5):2089.

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Scientific Sources

How does AprèsFlex® Boswellia serrata extract 100mg (20% AKBA) in 5-LOX Inhibitor with AprèsFlex® work?

AprèsFlex® 100mg provides 20% AKBA (acetyl-11-keto-beta-boswellic acid) for 5-LOX inhibition. Inhibits 5-lipoxygenase enzyme by 60-90% to reduce inflammatory leukotriene production. Clinical research demonstrates measurable benefits with consistent supplementation.

What makes this formula effective?

Supports joint comfort and mobility with 40-70% improvement in clinical trials. AprèsFlex® shows benefits within 5-7 days vs 30+ days for standard boswellia. The formulation provides research-backed dosages for optimal results.

Can I take 5-LOX Inhibitor with AprèsFlex® with other supplements?

This supplement is generally well-tolerated. Consult your healthcare provider if taking medications to ensure proper coordination.

How long before I see results?

Many users report benefits within 2-4 weeks. For comprehensive results, research suggests 8-12 weeks of daily supplementation.

What's the best way to take it?

Follow label directions. Taking with food may enhance absorption. Consistency is key for best results.

  • AprèsFlex® 100mg provides 20% AKBA (acetyl-11-keto-beta-boswellic acid) for 5-LOX inhibition - Supports health through clinically studied mechanisms
  • Inhibits 5-lipoxygenase enzyme by 60-90% to reduce inflammatory leukotriene production - Supports health through clinically studied mechanisms
  • Supports joint comfort and mobility with 40-70% improvement in clinical trials - Supports health through clinically studied mechanisms
  • AprèsFlex® shows benefits within 5-7 days vs 30+ days for standard boswellia - Supports health through clinically studied mechanisms
  • Supports healthy inflammatory response without GI side effects of NSAIDs - Supports health through clinically studied mechanisms
  • Promotes cartilage health and reduces matrix metalloproteinase activity - Supports health through clinically studied mechanisms
  • May support respiratory health through leukotriene pathway modulation - Supports health through clinically studied mechanisms
  • Supports vascular health and healthy endothelial function - Supports health through clinically studied mechanisms
  • Clinically studied AprèsFlex® standardized to optimal AKBA levels - Supports health through clinically studied mechanisms
  • Superior bioavailability compared to standard boswellia extracts - Supports health through clinically studied mechanisms
  • Adults seeking science-based nutritional support
  • Individuals with specific health goals
  • People interested in clinically researched ingredients
  • Those committed to wellness optimization
  • Adults addressing nutritional needs
  • Individuals seeking quality supplements
  • People interested in preventive health
  • Those valuing evidence-based supplementation
  • Adults supporting overall vitality
  • Individuals seeking targeted nutrition
  • Pregnant/nursing women without provider consultation
  • Individuals taking medications (consult physician)
  • People with known ingredient allergies
  • Those with serious conditions without supervision
  • Individuals scheduled for surgery within 2 weeks
  • Children under 18 unless directed by provider

How to Use 5-LOX Inhibitor with AprèsFlex®

  1. Read label and follow dosage
  2. Take with meal
  3. Maintain daily routine
  4. Store properly
  5. Stay hydrated
  6. Track progress
  7. Consult if on medications
  8. Allow 4-8 weeks
  9. Follow limits
  10. Store safely

Results: AprèsFlex® boswellia extract at 100mg daily (20% AKBA) improves joint function scores by 40-70%, reduces pain by 50-65%, and shows benefits within 5-7 days in osteoarthritis patients.

Citation: Sengupta K, et al. Int J Med Sci. 2010;7(6):366-377. doi:10.7150/ijms.7.366

Results: AKBA from boswellia inhibits 5-lipoxygenase enzyme activity by 60-90%, reducing pro-inflammatory leukotriene B4 production and supporting healthy inflammatory response.

Citation: Safayhi H, et al. J Pharmacol Exp Ther. 1992;261(3):1143-1146. PMID: 1602379

Results: AprèsFlex® demonstrates superior bioavailability with 52% higher AKBA absorption compared to standard boswellia extracts in pharmacokinetic studies.

Citation: Sengupta K, et al. Phytother Res. 2008;22(9):1278-1282. doi:10.1002/ptr.2465

Results: Boswellia AKBA reduces matrix metalloproteinases (MMPs) that degrade cartilage by 30-50%, supporting joint structure preservation and reducing osteoarthritis progression.

Citation: Roy S, et al. Evid Based Complement Alternat Med. 2006;3(3):301-308. doi:10.1093/ecam/nel024