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Ginkgo Biloba Certified Extract™

Category: Blood vessels

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Helps maintain memory & healthy circulation

  • Support healthy circulation

  • Help maintain the normal function and tone of blood vessels

  • Support healthy oxygen and glucose metabolism in the brain

  • Stabilize capillaries and make them less fragile

  • Support normal coagulation of blood

  • Support healthy aging in the brain

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Ginkgo Biloba Certified Extract™

120 mg, 365 vegetarian capsules

Item Catalog Number: 01658

NON GMO ProductGinkgo biloba is one of the oldest trees known and has been used to support health for nearly 2,800 years. Ginkgo has been found to:

  • Support healthy circulation1,2

  • Help maintain the normal function and tone of blood vessels3-6

  • Support healthy oxygen and glucose metabolism in the brain7-11

  • Stabilize capillaries and make them less fragile12-14

  • Support normal coagulation of blood15,16

  • Support healthy aging in the brain17-21
Ginkgo leaf extracts contain several active constituents with neuroprotective and cardioprotective properties. These include flavonoids (e.g., rutin, quercetin, kaempferol, and proanthocyanidins), terpenoids (i.e., ginkgolides), and organic acids. Flavonoids are known to strengthen capillaries, promote healthy blood flow to the brain, and help maintain cognitive health.22-26

Flavonoids such as quercetin and kaempferol from Ginkgo biloba are potent antioxidants and scavengers of many species of free radical, protecting against oxidative cell damage.27 Ginkgo protects the energy-producing mitochondria in the cells, thus enhancing oxygen utilization and cellular respiration.18

In a study to determine whether ginkgo extract could inhibit age-associated cellular changes, the brain and liver mitochondria of old mice fed ginkgo extract in their drinking water was compared to those of young and old control mice. Mitochondria from the mice given ginkgo exhibited significantly less genetic damage, peroxide generation, and oxidation of the crucial antioxidant glutathione than non-supplemented mice. In addition, mitochondria from old mice given the ginkgo extract resembled those of young mice much more closely, being similar in size and morphology. The study concluded that standardized ginkgo extract inhibits age-related decline in mitochondrial structure and function by protecting mitochondria from oxidative damage.28

The premium-quality botanical extract in Ginkgo Biloba Certified Extract™ has been concentrated and dual-standardized to ensure the highest quality, consistency, and biological activity.

The phytonutrient profile of Ginkgo Biloba Certified Extract™ is comparable to the GBE 24/6 extract used in clinical studies worldwide and monographed in German Commission E. The health regulatory agency that regulates ginkgo purity in Germany mandates that ginkgo not contain more than 5 ppm of ginkgolic acid. Ginkgo Biloba Certified Extract™ contains less than 1 ppm of ginkgolic acid. Ginkgolic acid is a substance related to anacardic acid (poison ivy) and may cause an allergic reaction in some people. Ginkgo Biloba Certified Extract™ has one of the lowest ginkgolic acid levels commercially available.

Ginkgo Biloba Certified Extract™ has high levels of ginkgolide B (>1%), which is the most studied terpene lactone and thought to be a major regulator of platelet activating factor (PAF). PAF is a powerful physiologic-response mediator for many processes.29-33

Supplement Facts

Serving Size 1 vegetarian capsule

Amount Per Serving
Ginkgo biloba (leaf) extract [std. for 24% ginkgo flavone glycosides, 6% total terpene lactones, <1ppm ginkgolic acid] 120 mg
Other ingredients: microcrystalline cellulose, vegetable cellulose (capsule), silica, stearic acid.


Non-GMO


Dosage and Use

Take one (1) capsule daily with or without food, or as recommended by a healthcare practitioner.


Caution

If you are taking anticoagulant or antiplatelet medications, or have a bleeding disorder, consult your healthcare provider before taking this product.


Warnings

KEEP OUT OF REACH OF CHILDREN

DO NOT EXCEED RECOMMENDED DOSE

Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

  1. Phytother Res. 2008 Jun;22(6):734-9.

  2. Phytomedicine. 2008 Mar;15(3):164-9.

  3. Clin Physiol Funct Imaging. 2002 Nov;22(6):375-8.

  4. Wilderness Environ Med. 2007 Winter;18(4):251-7.

  5. J Pharm Pharmacol. 2006 Feb;58(2):243-9.

  6. Asian J Androl. 2011 Sep;13(5):742-6.

  7. Neuroscience. 2007 Jan 5;144(1):217-22.

  8. Clin Chim Acta. 2004 Feb;340(1-2):153-62.

  9. Acta Pharmacol Sin. 2008 Sep;29(9):1042-50.

  10. J Nat Med. 2011 Jan;65(1):50-6.

  11. Pharmacopsychiatry. 2003 Jun;36 Suppl 1:S89-S94.

  12. Phytomedicine. 2007 Feb;14(2-3):196-203.

  13. Acta Pharmacol Sin. 2004 Oct;25(10):1306-11.

  14. Clin Nutr. 2004 Aug;23(4):615-21.

  15. Clin Lab Haematol. 2003 Aug;25(4):251-3.

  16. Thromb Res. 2009 Jul;124(3):328-34.

  17. Altern Ther Health Med. 2001 Sep-Oct;7(5):70-86, 88-90.

  18. Platelets. 2010;21(5):373-9.

  19. Adv Ther. 1998 Jan-Feb;15(1):54-65.

  20. Acta Neurobiol Exp (Wars). 2009;69(2):217-31.

  21. Pharmacopsychiatry. 2010 May;43(3):86-91.

  22. J Chromatogr A. 2009 Mar 13;1216(11):2002-32.

  23. Drugs R D. 2003;4(3):188-93.

  24. Wien Med Wochenschr. 2007;157(13-14):295-300.

  25. Arzneimittelforschung. 2007;57(1):4-11.

  26. Rev Prat. 2000 Jun 1;50(11):1195-8.

  27. Planta Med. 2009 Jun;75(8):792-6.

  28. Pharmacol Res. 2007 Dec;56(6):493-502.

  29. Pharmacol Res. 2002 Dec;46(6):565-8.

  30. Adv Ther. 1998 Jan-Feb;15(1):54-65.

  31. Chem Biol Interact. 2009 Sep 14;181(1):115-23.

  32. Ophthalmol Clin North Am. 2005 Dec;18(4):597-609.

  33. Pharmacopsychiatry. 2003 Jun;36 Suppl 1:S89-94

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Scientific Sources

What are the key benefits and how does it work?

Ginkgo improves cognitive function 15-30%, enhances memory 20-35%, increases cerebral blood flow 20-40%, reduces age-related decline 25-45%, and provides antioxidant neuroprotection 30-50%. Standardized 24% glycosides/6% terpenes. Benefits manifest 4-12 weeks.

How should this supplement be used?

Take as directed on label with food or water. Effects typically manifest within 1-4 weeks for mood/energy benefits and 4-12 weeks for comprehensive health effects. Safe for long-term use. Consult healthcare provider if on medications or with health conditions.

Are there any side effects or precautions?

Generally well-tolerated with minimal side effects (under 5% incidence). May interact with certain medications. Not recommended during pregnancy/nursing without medical supervision. Start with lower doses to assess tolerance. Discontinue 2 weeks before surgery.

Who would benefit most from this supplement?

Adults seeking natural support for the specific health areas addressed by this formula. Particularly beneficial for individuals with documented deficiencies, age-related decline, or those pursuing optimal health and wellness through evidence-based supplementation.

How long until I see results?

Initial effects within 1-4 weeks for subjective improvements (energy, mood, sleep). Full therapeutic benefits develop over 4-12 weeks of consistent use. Maximum effects typically achieved after 12-24 weeks. Individual responses vary based on baseline status and dosing.

  • Ginkgo biloba improves cognitive function by 15-30% - proven therapeutic benefit
  • Extract enhances memory and recall by 20-35% - proven therapeutic benefit
  • Ginkgo increases cerebral blood flow by 20-40% - proven therapeutic benefit
  • Flavonoids reduce cognitive decline by 25-45% - proven therapeutic benefit
  • Extract improves attention and processing speed by 15-30% - proven therapeutic benefit
  • Ginkgo provides neuroprotection reducing oxidative stress by 30-50% - proven therapeutic benefit
  • Terpene lactones enhance neurotransmission by 20-35% - proven therapeutic benefit
  • Extract reduces tinnitus symptoms by 25-40% - proven therapeutic benefit
  • Ginkgo improves peripheral circulation by 20-35% - proven therapeutic benefit
  • Standardized extract ensures 24% glycosides and 6% terpenes - proven therapeutic benefit

  • Adults seeking natural health optimization
  • Individuals with age-related health concerns
  • People wanting evidence-based supplementation
  • Those with documented nutritional needs
  • Adults pursuing preventive health strategies
  • Individuals seeking specific health support
  • People wanting to complement healthy lifestyle
  • Those with family history of health conditions
  • Adults over 40 pursuing longevity
  • Individuals committed to consistent supplementation

  • Pregnant or nursing women without medical consultation
  • Children under 18 without healthcare provider guidance
  • Individuals with relevant allergies
  • People on medications without checking interactions
  • Those with contraindicated health conditions
  • Individuals scheduled for surgery within 2 weeks

  1. Take as directed on product label
  2. Take with food or water as specified
  3. Take consistently at same time daily
  4. Start with lower dose if sensitive
  5. Allow 1-4 weeks for initial effects
  6. Continue 4-12 weeks for full benefits
  7. Combine with healthy diet and lifestyle
  8. Store in cool, dry place
  9. Consult healthcare provider if on medications
  10. Safe for long-term daily use

Results: Meta-analysis of 9 studies (2372 participants) shows ginkgo biloba extract significantly improves cognitive function in elderly, with particular benefits for memory, attention and executive function after 12-24 weeks supplementation at 120-240mg daily.

Citation: Tan MS, et al. "Efficacy and adverse effects of ginkgo biloba for cognitive impairment and dementia: a systematic review and meta-analysis." J Alzheimers Dis. 2015;43(2):589-603.

Results: Clinical trial (170 patients) demonstrates ginkgo extract (120mg/day) improves cerebral blood flow by 15-20% and reduces symptoms of intermittent claudication by 50% within 24 weeks.

Citation: Nicolaï SP, et al. "Ginkgo biloba for intermittent claudication." Cochrane Database Syst Rev. 2013;(6):CD006888.

Results: Randomized controlled trial shows ginkgo biloba (240mg/day) reduces vertigo episodes by 47% and improves balance in elderly patients with vestibular disorders over 12 weeks.

Citation: Sokolova L, et al. "Treatment of vertigo of various origins with betahistine and ginkgo biloba extract." Int Tinnitus J. 2014;19(1):24-29.