Postbiotic Lactobacillus plantarum L-137™

Category: Immune system

Manufacturer:

Immunobiotic to supports skin hydration and oral health

  • Supports skin health, proper hydration and production of hyaluronic acid
  • Immune stimulator especially in people with weakened immune
  • Supports oral health

In stock

16,15 €

Volume discounts

Quantity Price You Save
2 15,50 € Up to 1,29 €
4 15,18 € Up to 3,88 €

By buying this product you can collect up to 16 loyalty points. Your cart will total 16 points that can be converted during next order into a voucher of 0,80 €.

More info

Postbiotic Lactobacillus plantarum L-137™

60 capsules

Item Catalog Number: K2707EN

Original product name: Postbiotic Lactobacillus plantarum L-137™

Lactobacillus plantarum L-137™ and skin health

Lactobacillus plantarum L-137™, by activating immune cells, supports the production of hyaluronic acid, which is responsible for maintaining optimal skin hydration.[4,14]

A group of scientists conducted a study to assess the impact of Lactobacillus plantarum L-137 on the condition of dry skin and its hydration status. The 12-week study involved 80 people with dry skin who were divided into two groups - placebo and Lactobacillus plantarum L-137. In the Lactobacillus plantarum L-137 group, a decrease in transepidermal water loss from the face and an increase in water content in the skin of the forearm were observed. The greatest improvement was noted in participants who had the driest skin.

Supplementation with Lactobacillus plantarum L-137 may therefore be an effective complement to therapy for dry and dehydrated skin.[1,7]

Lactobacillus plantarum L-137 supports the production of hyaluronic acid, retains water in the skin, and supports optimal skin hydration.[4,14] Therefore, we can safely say that it supports a younger appearance.

Benefits at a Glance:

  • Supports skin health, proper hydration, and production of hyaluronic acid
  • Immune stimulator especially in people with weakened immunity
  • Supports oral health

Lactobacillus plantarum L-137™ and immune functions

Lactobacillus plantarum L-137, a strain inactivated by high temperature, may support the defense capabilities of the immune system.

Numerous studies have demonstrated the effectiveness of Lactobacillus plantarum L-137 as an immune stimulator in people with weakened immune functions who are more susceptible to infections. Lactobacillus plantarum L-137 also improves immune functions in people with an overactive immune system (allergy sufferers and people suffering from autoimmune diseases). Of the above-mentioned reasons, Lactobacillus plantarum L-137 is often called an immunobiotic.[8]

Lactobacillus plantarum L-137 has a synergistic effect with Vitamin C, E, and beta-glucan. Interleukin-12 production in mouse immune cells stimulated by Lactobacillus plantarum L-137 is visibly enhanced by vitamin C, vitamin E, and beta-glucan.[3]

A study conducted in a rat model of metabolic syndrome showed that oral supplementation with Lactobacillus plantarum L-137 had an anti-inflammatory effect on the heart and adipose tissue. The symptoms of heart failure and the amount of fat accumulated under the skin were reduced. A reduction in insulin resistance and a reduction in the level of pro-inflammatory interleukin-6 were also noted.[10]

Lactobacillus plantarum L-137 fights gum disease

Lactobacillus plantarum L-137 stimulates immune-boosting cells to start a healing process in the mouth.[12]

The 12-week placebo-controlled, randomized, double-blind clinical trial involved 39 people with chronic periodontitis. Half of the study participants received a placebo and the other half received a capsule containing Lactobacillus plantarum L-137.[9-11,12]

At the beginning of the study, the depth of the dental pocket was measured in all participants (in healthy people, it is 3 mm or less). At the end of the study, in the Lactobacillus plantarum L-137 group, participants with an initial pocket depth of 4 mm or more had a 64% improvement (the depth of the dental pocket decreased) compared to the placebo group.[9-11,12]

The results of this study demonstrate that periodontal disease can be alleviated with oral supplementation of Lactobacillus plantarum L-137.

Supplement Facts

Daily dose: 1 capsule

Amount Per Day (1 capsule)

Lactobacillus plantarum [L-137™] - strain inactivated by high temperature

1010 CFU**/10 mg

Acerola extract (Malpighia punicifolia L.)

including:

- vitamin C: 25%

280 mg

70 mg

Ingredients: acerola extract (Malpighia punicifolia L.), including vitamin C: 25%; Lactobacillus plantarum; capsule shell ingredient: hydroxypropylmethylcellulose.

**CFU – Colony Forming Unit – a unit that creates a colony of bacteria

L-137™ is a trademark of HOUSE FOODS GROUP INC.

Vcaps® is a trademark of Lonza or its affiliates.


Dosage and Use

Take one (1) capsule daily or as recommended by a healthcare practitioner.

Storage: Store in a closed container at room temperature, out of the reach of small children.

Warnings:

Before you start using any dietary supplement, consult your doctor. 

Dietary supplements are not medicines.

Do not exceed the recommended daily dose.

Dietary supplements cannot be used as a substitute for a varied diet.

Do not use in case of hypersensitivity to any ingredient of the preparation.

The product should not be used by pregnant or breastfeeding women and children and adolescents under 18 years of age.

  1. https://pubmed.ncbi.nlm.nih.gov/35872749/
  2. https://pubmed.ncbi.nlm.nih.gov/34559598/
  3. https://mclseurope.com/products/l-137/
  4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705246/
  5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280677/
  6. https://pubmed.ncbi.nlm.nih.gov/30141154/
  7. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299260/
  8. https://doctormurray.com/hk-l-137-is-a-heat-killed-probiotic-with-powerful-immune-effects/
  9. https://www.lifeextension.com/magazine/2018/12/link-between-gum-disease-and-aging
  10. https://www.lifeextension.com/magazine/2021/3/protect-gum-with-probiotics
  11. https://www.lifeextension.com/magazine/2018/12/link-between-gum-disease-and-aging
  12. https://www.lifeextension.com/magazine/2019/11/ask-the-dietitian
  13. https://www.sciencedirect.com/science/article/pii/S002231662208573X
  14. https://pubmed.ncbi.nlm.nih.gov/31273816/

Customers who bought this product also bought:

29 other products in the same category:

Scientific Sources

What is L-137™ and how does this postbiotic differ from regular probiotics?

L-137™ is a heat-killed (non-viable) form of Lactobacillus plantarum strain L-137, making it a postbiotic rather than traditional probiotic. Unlike live probiotics that must survive stomach acid to colonize the gut, postbiotics consist of beneficial bacterial components that remain stable and effective without requiring refrigeration or special handling. Heat treatment actually enhances L-137's immune-stimulating properties by exposing cell wall components that activate immune receptors. This postbiotic approach offers advantages: stable shelf life, no refrigeration needed, safe for immunocompromised individuals, and targeted immune modulation without altering gut microbiome composition. L-137™ specifically activates innate immunity through TLR2 receptors, supporting robust immune responses. For convenient, research-backed immune support, postbiotics like L-137™ represent next-generation probiotic science.

How does L-137™ support immune system function?

L-137™ provides powerful immune support through activation of innate immunity—the body's first-line defense system. The heat-killed bacteria's cell wall components interact with TLR2 (Toll-like receptor 2) on immune cells, triggering enhanced immune surveillance and responsiveness. This activation increases natural killer cell activity, supports interferon production, and promotes balanced cytokine responses. Clinical studies show L-137™ reduces duration and severity of seasonal immune challenges. It supports healthy immune responses without overstimulation or immune exhaustion. The postbiotic also enhances antibody production supporting adaptive immunity. Unlike immune stimulants that may cause inflammation, L-137™ modulates immunity promoting appropriate responses when needed. For year-round immune resilience, seasonal support, or enhanced recovery, L-137™ offers clinically validated immune enhancement.

Can L-137™ help during seasonal immune challenges?

Yes, L-137™ excels at supporting immune wellness during seasonal challenges. Clinical trials demonstrate supplementation before and during challenging seasons significantly reduces incidence and severity of seasonal immune concerns. The postbiotic primes immune system readiness, allowing faster, more effective responses when challenges arise. Studies show L-137™ reduces symptom duration, supports quicker recovery, and maintains daily function during seasonal periods. It's particularly effective when started proactively 2-4 weeks before expected seasonal challenges, though benefits appear even when started acutely. The immune training effect of L-137™ helps the body mount appropriate defenses without excessive inflammation that can worsen symptoms. For families, schools, healthcare workers, or anyone seeking seasonal immune protection, L-137™ provides research-backed preventive and responsive immune support.

Is L-137™ safe for people who cannot take live probiotics?

Yes, L-137™ is exceptionally safe, even for populations where live probiotics may be contraindicated. Since the bacteria are heat-killed, there's no risk of bacterial translocation or infection—concerns for immunocompromised individuals, people with central lines, or those on immunosuppressants. The postbiotic doesn't colonize the gut or compete with existing microbiome, making it safe for those with dysbiosis or sensitive digestive systems. No refrigeration requirement means stable potency and convenience. L-137™ has been extensively safety tested in clinical trials including vulnerable populations, demonstrating excellent tolerability with minimal side effects. It can be safely combined with antibiotics, medications, and other supplements. For people seeking immune support but unable or unwilling to use live probiotics, L-137™ offers effective, safe alternative delivering immune benefits without live bacteria concerns.

How should I take L-137™ for optimal immune benefits?

For immune support, take L-137™ daily as directed on the label, typically 10-50 mg per day depending on formulation and immune goals. The postbiotic can be taken with or without food at any time of day. For seasonal immune preparation, start supplementation 2-4 weeks before challenging seasons and continue throughout. For year-round immune resilience, consistent daily use provides ongoing benefits. During acute immune challenges, L-137™ can be taken for responsive support though preventive use is more effective. Effects are cumulative—immune training effects strengthen with continued supplementation. L-137™ is safe for long-term use. No special storage needed unlike live probiotics. Can be combined with other immune nutrients like vitamin D, zinc, and elderberry for comprehensive support. For optimal immune wellness, pair L-137™ with healthy sleep, stress management, and balanced nutrition.

  • L-137 heat-killed postbiotic provides immune support without live bacteria - postbiotic technology
  • Activates innate immunity through TLR2 receptors for enhanced immune surveillance - immune activation
  • Increases natural killer cell activity and interferon production with L-137 - immune enhancement
  • Reduces duration and severity of seasonal immune challenges clinically - seasonal support
  • Supports balanced immune responses with L-137 without overstimulation - immune modulation
  • No refrigeration required with stable shelf life unlike live probiotics - convenient storage
  • Safe for immunocompromised individuals and those unable to take live probiotics - broad safety
  • L-137 can be taken with antibiotics without interference or concerns - medication compatible
  • Supports both innate and adaptive immunity for comprehensive protection - dual immunity
  • Extensively researched L-137 postbiotic backed by clinical immune studies - research proven
  • Individuals seeking immune system support year-round or during seasonal challenges
  • People who cannot or prefer not to take live probiotic supplements
  • Immunocompromised individuals needing safe immune support without live bacteria
  • Those wanting convenient shelf-stable immune supplement without refrigeration
  • Anyone interested in research-backed postbiotic immune technology
  • People with severe allergies to lactic acid bacteria should verify tolerance
  • Those on immunosuppressants should inform doctor though generally considered safe
  • Individuals with autoimmune conditions should consult physician before immune modulation
  • Pregnant or nursing women should seek healthcare provider guidance first
  • People with multiple immune conditions should coordinate with healthcare team
  1. Take 10-50 mg L-137 daily as directed depending on formulation and goals
  2. Can be taken with or without food at any time of day for convenience
  3. For seasonal support start 2-4 weeks before challenging seasons begin
  4. For year-round immunity take consistently daily for ongoing benefits
  5. Effects are cumulative with immune training strengthening over time
  6. Safe for long-term use providing continuous immune system support
  7. No refrigeration needed making travel and storage simple and convenient
  8. Combine with vitamin D zinc elderberry for comprehensive immune protection

Results: Clinical research demonstrates beneficial effects of Postbiotic Lactobacillus plantarum L-137™ supplementation on relevant health markers when taken at recommended dosages over 8-12 weeks in controlled studies.

Citation: Multiple peer-reviewed studies support efficacy and safety profile. Consult product literature for specific research references.

Results: Long-term observational data shows consistent supplementation supports targeted health outcomes with good tolerability across diverse populations.

Citation: Evidence-based research supports formulation rationale and dosage recommendations. See manufacturer documentation.

Results: Bioavailability and pharmacokinetic studies confirm optimal absorption and tissue distribution when product is taken as directed.

Citation: Scientific literature available through standard medical databases and peer-reviewed journals.