Nattokinase 100 mg NSK-SD®

Nattokinase 100 mg NSK-SD®

60 capsules

Item Catalog Number: K1014EN

Original product name: Nattokinaza 100 mg NSK-SD®

In recent years, Natto has gained the reputation of a superfood. This traditional Japanese dish made from fermented soybeans has a number of health benefits. Natto's health benefits are due to the presence of an enzyme - nattokinase (discovered in the sticky part of Natto). Nattokinase is an enzyme produced by a certain strain of Bacillus subtilis bacteria during the fermentation of soybeans. Nattokinase gained popularity due to its beneficial cardiovascular health effects. This enzyme also helps maintain the balance of the intestinal microbiome.

Patented  and safe Nattokinase NSK-SD®

JAPAN BIO SCIENCE LABORATORY has patented a unique modern technology enabling the removal of vitamin K from Nattokinase NSK-SD®.

Vitamin K interacts with warfarin and other blood thinners. Nattokinase NSK-SD® is safe for use in people taking warfarin or other anticoagulants because it does not contain vitamin K.[2,33]

JAPAN BIO SCIENCE LABORATORY is the only Japanese company that can export Nattokinase without vitamin K2.[2,33]

Benefits at a Glance:

• Supports circulatory system and shows antithrombotic activity

• Shows anti-atherosclerotic and lipid-lowering effects

• Shows antihypertensive effects

• Shows anticoagulant effects

• Safe for people using anticoagulants

Nattokinase supports Circulatory system and shows Antithrombotic activity

Nattokinase has beneficial effects in the prevention and treatment of cardiovascular diseases.[3,4] For many years, scientists, especially from Japan, Korea and China, have been constantly researching Nattokinase's role in the prevention and treatment of cardiovascular diseases.[3-6] Nattokinase is considered as safe, powerful, low cost, and all-natural supplement to support heart and cardiovascular health.[3-4,6-9]

Both, animal and human studies has shown beneficial effects of Nattokinase. It supports the circulatory system by thinning the blood and dissolving blood clots.[3,4,10-15] Nattokinase shows an effect on both oxidative injury-mediated arterial thrombosis [3,4,16,17] and inflammation-induced venal thrombosis.

Nattokinase as anti-atherosclerotic and lipid-lowering agent

Atherosclerosis, which is primary cause of many cardiovascular diseases, is also a cause of heart diseases and stroke. Nattokinase shows promising anti-atherosclerotic and lipid-lowering effects. [3-4,18]

Many studies showed anti-atherosclerotic and lipid-lowering effects of Nattokinase supplementation. In a clinical study on rats,[3,4,16,19] Nattokinase and the natto extract supplementation suppressed endothelial's intimal thickening in rats with diagnosed endothelial injury. Other study demonstrated that NK prevented arteriosclerosis by its direct antioxidant effect leading to reduced lipid peroxidation and improved lipid metabolism (inhibition of LDL oxidation).[3,4,20] 

One of clinical trials demonstrated that after 26 weeks of Nattokinase supplementation, there was a significant reduction in CCA intima-media thickness (CCA-IMT) and carotid plaque size when compared with the baseline before treatment.[3,4,5,21] Nattokinase may ba a great alternative to statins, a commonly used drug to reduce atherosclerosis.

In animal models, nattokinase showed a hypolipidaemic effect and can significantly reduce the increased serum triglycerides, total cholesterol, and LDL cholesterol levels.[3,4,5,22]

Nattokinase as an antihypertensive agent

One study[3,4,24] suggested that nattokinase consumption for 8 weeks caused beneficial changes to blood pressure in patients having hypertension.

Long-term use of antihypertensive drugs causes side effects,[3,4,25]so nattokinase may be a promising alternative for the management of hypertension in patients with diagnosed cardiovascular diseases. Nattokinase supplementation may be a successful additional treatment strategy for patients with hypertension.[3,4,26] Of course, each action requires consultation with the attending physician.

Nattokinase as an anticoagulant effects

One study compared the antithrombotic effects of aspirin and nattokinase. In both in vitro and in vivo tests, nattokinase showed excellent platelet aggregation inhibitory effects.[3,4,27] Long-term use of aspirin comes with serious gastrointestinal side effects and bleeding.[3,4,29] Nattokinase does not cause such a side effects.[3,4,28,29] It may therefore prove to be a very effective, natural and body-friendly way to improve blood flow without the unpleasant side effects from the digestive system associated with long-term aspirin supplementation. [3,4,28]

Supplement Facts

Daily dose: 1 capsule

Contains soy

NSK-SD® is a trademark of Japan Bio-Science Laboratories.

Dosage and Use

Take one (1) capsule daily or as recommended by a healthcare practitioner.

Storage: Store in a closed container at room temperature, out of the reach of small children.

Warnings:

Before you start using any dietary supplement, consult your doctor. 

Dietary supplements are not medicines.

Do not exceed the recommended daily dose.

Dietary supplements cannot be used as a substitute for a varied diet.

Do not use in case of hypersensitivity to any ingredient of the preparation.

The product should not be used by pregnant or breastfeeding women and children and adolescents under 18 years of age.