Collagen UC-II®

Category: Joints

Manufacturer:

UC-II Collagen protects against arthritis and more

  • A Type II Collagen Protects Against Arthritis

  • Relieves osteoarthritis pain
  • Relieves joint and muscle pain
  • Relieves exercise-induced joint pain 
  • Supports joint health and improves joint flexibility
  • Restores healthy function in aging joints

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Collagen UC-II®

60 capsules

Item Catalog Number: K0956EN

Original product name: Kolagen UC-II®

Collagen UC-II

Collagen UC-II contains a patented form of undenatured type II collagen derived from chicken sternum. UC-II Collagen protects against arthritis as well as relieves osteoarthritis pain. Moreover, this undenatured colagen tpy II may relieve joint and muscle pain and improve joint flexibility. It also relieves exercise-induced joint pain. 

Benefits at a Glance:

  • A Type II Collagen Protects Against Arthritis

  • Relieves osteoarthritis pain
  • Relieves joint and muscle pain
  • Relieves exercise-induced joint pain 
  • Supports joint health and improves joint flexibility
  • Restores healthy function in aging joints

UC-II, rheumatoid arthritis and osteoarthritis

Arthritis afflicts millions if people around the world. Most common types of arthritis are osteoarthritis and rheumatoid arthritis. Osteoarthritis of the knee and hip is a growing health concern and is the most common forms of arthritis.[5,6,7]

Studies have shown that undenatured type II collagen (UC-II) is effective in the treatment of rheumatoid arthritis, and preliminary human and animal trials have shown it to be also effective in treating osteoarthritis.[4]

A randomized, double-blind, placebo-controlled study on UC-II colagen

A group of scientists conducted a randomized, double-blind, placebo-controlled study in healthy volunteers about undenatured type II collagen (UC-II®) for joint support. [1,2]

In a 120-day clinical trial, 55 healthy volunteers who experienced knee pain after a standardized endurance test were randomly assigned to the UC-II group or to the placebo group. The UC-II group received 40 mg of undenatured type II collagen every day for 120 days.[1,2]

Daily supplementation with 40 mg UC-II was well tolerated and didn't caused any adverse effects. A daily dose of 40 mg of UC-II improved knee extension in healthy volunteers. Moreover, UC-II has also shown the potential to prolong pain-free periods of intense exercise and alleviate joint pain that sometimes occurs as a result of such activity. [1,2]

Supplement Facts

Daily dose: 1 capsule

Amount Per Day (1 capsule)

Standardized chicken cartilage /UC-II®/, including:

total type II collagen:

40 mg

10 mg

Ingredients: filling substance: microcrystalline cellulose, standardized chicken sternum cartilage incl. type II collagen, capsule shell: hydroxypropyl methylcellulose


UC-II® is a registered trademark of InterHealth N.I.

Dosage and Use

Take one (1) capsule daily or as recommended by a healthcare practitioner.

Storage: Store in a closed container at room temperature, out of the reach of small children.

Warnings:

Before you start using any dietary supplement, consult your doctor. 

Dietary supplements are not medicines.

Do not exceed the recommended daily dose.

Dietary supplements cannot be used as a substitute for a varied diet.

Do not use in case of hypersensitivity to any ingredient of the preparation.

The product should not be used by pregnant or breastfeeding women and children and adolescents under 18 years of age.

  1. J P Lugo, Z M Saiyed, F C Lau, J P L Molina, M N Pakdaman, A N Shamie & J K Udani "Undenatured type II collagen (UC-II®) for joint support: a randomized, double-blind, placebo-controlled study in healthy volunteers"
  2. https://jissn.biomedcentral.com/articles/10.1186/1550-2783-10-48
  3. https://www.lifeextension.com/magazine/2013/10/novel-mechanism-protects-against-arthritis
  4. D C Crowley,F C. Lau, P Sharma, M Evans, N Guthrie, M Bagchi, D Bagchi, D K. Dey, and S P. Raychaudhuri "Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial"
  5. Braham R, Dawson B, Goodman C. The effect of glucosamine supplementation on people experiencing regular knee pain. Br J Sports Med. 2003;37:4549.
  6. Cote LG. Management of osteoarthritis. J Am Acad Nurse Pract. 2001;13:495–501.
  7. Arthritis Foundation. http://www.arthritis.org/conditions/DiseaseCenter/default.asp.
  8. https://www.lonza.com/uc-ii/-/media/Microsites/UC-II/Documents/UCII_WhitePaper.PDF

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