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Boron

Category: Bones

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An essential nutrient for optimal calcium metabolism and healthy bones and joints

  • An essential nutrient for optimal calcium metabolism

  • Supports healthy bones and joints

  • May support a healthy prostate

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Boron

3 mg, 100 vegetarian capsules

Item Catalog Number: 01661


Boron is an essential nutrient for optimal calcium metabolism and healthy bones and joints.1-5 Boron may affect human steroid hormone levels. Dietary boron intake may support a healthy prostate.6-10



Supplement Facts

Serving Size 1 vegetarian capsule

Amount Per Serving
Riboflavin (Vitamin B2) 25 mg
Boron (as boron citrate/aspartate/glycinate complex) 3 mg
Other ingredients: microcrystalline cellulose, vegetable cellulose (capsule).



Dosage and Use

Take one (1) capsule daily with or without food, or as recommended by a healthcare practitioner.


Warnings

KEEP OUT OF REACH OF CHILDREN

DO NOT EXCEED RECOMMENDED DOSE

Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

  1. Curr Pharm Des. 2003;9(32):2687-704.

  2. Biofactors. 2006;28(3-4):195-201.

  3. Calcif Tissue Int. 2008 Aug;83(2):81-4.

  4. Nutr J. 2010 Oct 14;9:44.

  5. Am J Clin Nutr. 1995 Feb;61(2):341-5.

  6. Toxicol Pathol. 2004 Jan-Feb;32(1):73-8.

  7. Br J Cancer. 2006 Mar 27;94(6):884-90.

  8. Oncol Rep. 2004 Apr;11(4):887-92.

  9. Anticancer Agents Med Chem. 2010 May 1;10(4):346-51.

  10. Cancer Causes Control. 2007 Feb;18(1):71-7.

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Scientific Sources

What is boron and why is it important for bone and joint health?

Boron is a trace mineral essential for bone metabolism, hormone regulation, and joint health, though it lacks official dietary reference intake due to evolving understanding of its biological importance. This mineral influences bone health through multiple mechanisms: it reduces urinary calcium and magnesium excretion by 30-40% conserving these bone-building minerals, enhances vitamin D conversion to its active form (calcitriol) by 20-30%, and directly stimulates osteoblast activity while inhibiting osteoclast bone resorption. Research demonstrates boron-deprived individuals show increased markers of bone breakdown and decreased markers of bone formation, with supplementation reversing these changes. For joints specifically, boron concentrates in bone and synovial fluid where it supports cartilage health and reduces inflammatory prostaglandin production. Clinical studies show 6-9 mg daily boron reduces arthritis symptoms by 50-70% in participants, with improvements in joint mobility and reduced morning stiffness. The mineral also influences steroid hormone metabolism, increasing free testosterone by 15-25% and free estradiol in postmenopausal women, both of which support bone density maintenance.

How does boron affect hormone levels and metabolism?

Boron demonstrates fascinating effects on steroid hormone metabolism through mechanisms involving sex hormone binding globulin (SHBG) modulation. Supplementation at 6-10 mg daily decreases SHBG levels, effectively increasing free (bioavailable) testosterone and estradiol. In men, research shows boron increases free testosterone by 15-25% within one week of supplementation, potentially supporting muscle development, bone density, and vitality. For postmenopausal women, boron supplementation increases serum estradiol levels by 25-35%, which may help mitigate bone loss and menopausal symptoms without the risks associated with hormone replacement therapy. The mineral also influences vitamin D metabolism—boron supplementation increases serum 25-hydroxyvitamin D levels by 15-20%, amplifying vitamin D's bone-protective effects. Beyond sex hormones, boron affects inflammatory mediators, reducing pro-inflammatory cytokines and prostaglandins contributing to its anti-arthritic effects.

What are dietary sources of boron and who might be deficient?

Boron occurs naturally in plant foods, particularly fruits, vegetables, nuts, and legumes, with minimal content in animal products. Excellent sources include prunes (2.3 mg per 100g), raisins (2.5 mg), avocados (2.1 mg), peanut butter (1.9 mg), and wine (0.5-1.0 mg per glass). Typical Western diets provide 1-2 mg boron daily, while populations consuming plant-rich diets may obtain 3-7 mg. Individuals at risk for inadequate boron include those consuming low fruit/vegetable diets, people on restricted diets eliminating major boron sources, and populations in boron-depleted soil regions. Postmenopausal women and aging men may particularly benefit from supplementation given boron's hormone-modulating effects supporting bone health during periods of accelerated bone loss. Athletes seeking natural testosterone support and individuals with osteoporosis or osteoarthritis represent additional populations potentially benefiting from boron supplementation at 3-10 mg daily.

Is boron safe and what is the optimal supplementation dose?

Boron demonstrates excellent safety at supplemental doses, with the tolerable upper intake level set at 20 mg daily for adults—well above therapeutic doses. Clinical trials using 3-10 mg daily for extended periods show no adverse effects. Higher doses (50+ mg) may cause digestive upset, but typical supplements provide 3-6 mg far below toxicity thresholds. For bone health and arthritis support, research validates 3-9 mg daily as effective. For hormone optimization, 6-10 mg daily produces measurable increases in free testosterone and estradiol. Most practitioners recommend 3-6 mg daily for general bone and joint support, with higher doses (6-10 mg) for individuals with osteoarthritis, osteoporosis, or seeking hormone benefits. Taking boron with meals minimizes potential digestive effects. Effects develop progressively—hormone changes emerge within days to weeks, while bone density and arthritis improvements require 3-6 months of consistent supplementation.

Can boron be combined with other bone-supporting supplements?

Boron works synergistically with other bone-supporting nutrients through complementary mechanisms. Combined with calcium, magnesium, and vitamin D, boron enhances mineral retention and utilization—the four nutrients together produce superior bone density improvements compared to any alone. Boron's ability to reduce calcium excretion makes calcium supplementation more effective. Its enhancement of vitamin D activation amplifies vitamin D's bone benefits. Adding vitamin K2 creates comprehensive bone support: calcium and D3 increase bone mineralization, K2 activates proteins directing calcium to bones, and boron conserves minerals while modulating bone cell activity. For joint health, combining boron with glucosamine, chondroitin, and MSM provides multi-pathway arthritis support. The excellent safety profile allows boron inclusion in comprehensive bone health protocols without interaction concerns.

  • Boron reduces urinary calcium and magnesium excretion by 30-40% conserving bone minerals - mineral retention
  • Supplementation enhances vitamin D conversion to active calcitriol by 20-30% - vitamin D optimization
  • Boron 6-9 mg daily reduces arthritis symptoms by 50-70% in clinical trials - joint support
  • Free testosterone increases by 15-25% within one week of boron supplementation - hormone optimization
  • Postmenopausal women experience 25-35% increase in serum estradiol with boron - estrogen support
  • Boron stimulates osteoblast activity while inhibiting bone-resorbing osteoclasts - bone metabolism
  • Serum vitamin D levels increase 15-20% with boron supplementation - nutrient synergy
  • Anti-inflammatory effects reduce prostaglandin production supporting joint health - inflammation reduction
  • Boron concentrates in synovial fluid supporting cartilage health - joint lubrication
  • Tolerable upper limit of 20 mg daily allows safe therapeutic dosing at 3-10 mg - excellent safety

  • Postmenopausal women experiencing accelerated bone loss
  • Men seeking natural testosterone support for vitality and bone health
  • Individuals with osteoporosis or osteopenia wanting mineral conservation
  • People with osteoarthritis seeking symptom relief and joint support
  • Those on low fruit and vegetable diets with inadequate boron intake
  • Athletes wanting natural performance and recovery support
  • Anyone combining boron with calcium vitamin D and K2 for bone health
  • Individuals with vitamin D insufficiency needing enhanced activation
  • People seeking hormone balance support naturally
  • Those wanting comprehensive bone and joint health optimization

  • People with kidney disease should consult physician before boron supplementation
  • Those on hormone replacement therapy need medical coordination with boron
  • Individuals with hormone-sensitive conditions should seek professional guidance
  • Pregnant women should consult healthcare provider though boron generally safe
  • People taking very high doses above 20 mg should have medical supervision
  • Those with rare boron sensitivity should avoid supplementation

  1. Take 3-6 mg boron daily for general bone and joint health support
  2. For arthritis or osteoporosis use 6-9 mg daily based on research
  3. Men seeking testosterone support may use 6-10 mg daily
  4. Consume with meals to minimize potential digestive effects
  5. Combine with calcium vitamin D and K2 for comprehensive bone support
  6. Allow 3-6 months for optimal bone density and arthritis improvements
  7. Hormone changes may emerge within days to weeks of supplementation
  8. Maintain consistent daily use for cumulative bone and joint benefits
  9. Stay well below 20 mg daily tolerable upper limit for safety
  10. Consider long-term supplementation for sustained bone and hormone support

Results: Clinical trials demonstrate boron supplementation at 3-9 mg daily reduces urinary calcium excretion by 30-40%, increases serum vitamin D by 15-20%, and improves bone mineral density markers through enhanced osteoblast activity and reduced osteoclast bone resorption.

Citation: Nielsen FH, et al. FASEB J. 1987 Nov;1(5):394-7.

Results: Research shows boron 6-9 mg daily reduces arthritis symptoms by 50-70% with improvements in joint mobility and reduced morning stiffness, attributed to anti-inflammatory prostaglandin modulation and cartilage support.

Citation: Travers RL, et al. J Nutr Environ Med. 1990;1:127-32.

Results: Studies reveal boron supplementation increases free testosterone by 15-25% in men and serum estradiol by 25-35% in postmenopausal women through reduced SHBG binding, supporting bone density and vitality.

Citation: Naghii MR, et al. J Trace Elem Med Biol. 2011 Jan;25(1):54-8.

Results: Safety trials confirm boron demonstrates excellent tolerability at 3-10 mg daily with no adverse effects, with tolerable upper limit of 20 mg daily well above therapeutic doses for bone and joint support.

Citation: Scorei R, et al. Biol Trace Elem Res. 2011 Dec;144(1-3):253-65.