Citicoline (CDP-Choline)

Category: Brain, memory and concentration

Manufacturer:

  • Encourages the synthesis of neurotransmitters in the brain
  • Supports healthy cognition & attention
  • Supports overall memory function & mood

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Citicoline (CDP-Choline)

60 vegetarian capsules

Item Catalog Number: 01659

Choline helps us produce a neurotransmitter that facilitates communication between neurons—a basic part of healthy brain function.

Power Up Your Brain

Choline is needed by our brains to produce acetylcholine, a neurotransmitter that facilitates communication between neurons. Unfortunately, our brain cells absorb less choline as we age. Our Citicoline (CDP-Choline) provides a form of choline that readily passes through the blood-brain barrier (BBB) directly into the brain, where cells can easily use it to nourish cellular membranes and support neurotransmitter production.

Choline is a substance needed by the brain to produce acetylcholine, a major brain/motor neuron neurotransmitter that facilitates the transmission of impulses between neurons. A substantial portion of the population consumes inadequate amounts of choline however, and dietary intake of the nutrient becomes increasingly important for brain health as we age.1,2

Benefits at a glance:

  • Encourages the synthesis of neurotransmitters in the brain
  • Supports healthy cognition & attention
  • Supports overall memory function & mood

What is CDP-choline?

CDP-choline stands for cytidine-5’-diphosphate choline, also known as citicoline. This form of choline readily passes through the blood-brain barrier (BBB) directly into the brain tissue.3 CDP-choline encourages the synthesis of neurotransmitters, particularly acetylcholine, in the brain, which is believed to explain many of its beneficial effects.3

The science of CDP-choline

CDP-choline is also a neuroprotectant and a promoter of neuroplasticity, with a track record of supporting healthy cognition, memory and overall function in numerous clinical trials.3-5

In addition to its clinically studied brain power benefits in older adults, low doses of citicoline have been shown to support a healthy mood.6 CDP-choline also supports phosphatidylcholine production, an important phospholipid for nerve growth, function, and cellular membrane repair.3

Supplement Facts

Serving Size 1 vegetarian capsule

Amount Per Serving

Citicoline (as citicoline monosodium salt)

250 mg

Other ingredients: vegetable cellulose (capsule), microcrystalline cellulose, silica, vegetable stearate.

Gluten-free
GMO-free
Vegetarian

Dosage and Use

Take one (1) capsule daily, or as recommended by a healthcare practitioner.

Warnings:

Before you start using any dietary supplement, consult your doctor. 

Dietary supplements are not medicines.

Do not exceed the recommended daily dose.

Dietary supplements cannot be used as a substitute for a varied diet.

Do not use in case of hypersensitivity to any ingredient of the preparation.

The product should not be used by pregnant or breastfeeding women and children and adolescents under 18 years of age.

  1. Jama. 1995;274(11):902-7.
  2. Nutrients. 2017;9(8)
  3. Rev Neurol. 2016;63(S03):S1-s73.
  4. Clin Interv Aging. 2015;10:1421-9.
  5. Rom J Ophthalmol. 2017;61(3):152-158.
  6. Clin Neuropharmacol. 2017;40(1):1-5.

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Scientific Sources

What is Citicoline (CDP-Choline) and how does it support health?

This premium supplement provides comprehensive support through clinically researched mechanisms. Citicoline has been extensively studied for its health benefits and effectiveness in supporting overall wellness and vitality through multiple pathways.

How does Citicoline work in the body?

Citicoline works through evidence-based mechanisms supporting cellular function and metabolic processes. Clinical research demonstrates significant benefits for health maintenance with consistent supplementation providing optimal support.

What health benefits does this supplement provide?

This supplement supports multiple aspects of health and wellness through researched ingredients. Users experience improvements in vitality function and overall quality of life with regular supplementation as demonstrated in clinical trials.

What makes this formulation superior to standard supplements?

This product uses premium standardized extracts with enhanced bioavailability and consistent potency. The formulation includes clinically studied ingredients at research-backed dosages ensuring optimal effectiveness and reliable health benefits.

How should I take this supplement for optimal results?

Take as directed on the product label for optimal health benefits. Consistent daily use provides best results as benefits accumulate over time. Combine with healthy lifestyle practices including balanced nutrition and regular physical activity.

  • Citicoline supports brain energy metabolism and ATP production in neurons - cognitive energy
  • Enhances memory formation with citicoline and acetylcholine synthesis - memory support
  • Citicoline promotes phosphatidylcholine production for neuronal membrane repair - brain structure
  • Supports focus and attention with citicoline and dopamine modulation - concentration
  • Citicoline provides neuroprotection against oxidative stress and damage - brain protection
  • Enhances neural communication with citicoline and neurotransmitter support - synaptic function
  • Citicoline supports cognitive function during aging and mental decline - aging support
  • Improves mental clarity with citicoline and cerebral blood flow - clarity enhancement
  • Citicoline supports post-stroke recovery and neurological rehabilitation - recovery support
  • Clinically studied citicoline with proven cognitive enhancement effects - research proven
  • Individuals seeking comprehensive health and wellness support naturally
  • People wanting to maintain vitality and optimal function with aging
  • Those interested in research-backed nutritional supplementation
  • Adults seeking proactive health maintenance and longevity support
  • Anyone wanting premium quality standardized health supplements
  • Pregnant or nursing women should consult healthcare provider before use
  • People on medications should verify compatibility with physician
  • Those with medical conditions should seek professional guidance first
  • Individuals with allergies should check ingredient list carefully
  • People scheduled for surgery should discontinue as advised by doctor
  1. Take as directed on product label for optimal health benefits
  2. Take with meals to enhance absorption and minimize effects
  3. Maintain consistent daily use as benefits accumulate over time
  4. Allow adequate time for full effects to develop with supplementation
  5. Combine with balanced diet exercise and healthy lifestyle practices
  6. Stay well hydrated throughout day to support effectiveness
  7. Monitor your response and adjust timing as needed for results
  8. Store properly to maintain potency and effectiveness of ingredients

Results: Clinical trials demonstrate citicoline supplementation significantly improves memory and cognitive function, with studies showing enhanced verbal memory, attention, and processing speed in adults taking 250-500 mg daily for 12 weeks.

Citation: McGlade E, et al. Food Nutr Sci. 2012;3(6):769-773.

Results: Research shows citicoline supports brain energy metabolism increasing ATP production by 14% and enhancing phospholipid synthesis by 26% in human brain tissue with supplementation.

Citation: Silveri MM, et al. NMR Biomed. 2008 Nov;21(10):1066-75.

Results: Studies indicate citicoline provides neuroprotection and supports recovery after stroke, with clinical trials showing reduced neurological deficits and improved functional outcomes in stroke patients receiving citicoline therapy.

Citation: Dávalos A, et al. Stroke. 2012 Oct;43(10):2850-7.

Results: Clinical research confirms citicoline enhances focus and attention in healthy adults, with studies demonstrating improved sustained attention, reduced omission errors, and enhanced cognitive performance during demanding tasks.

Citation: Spiers PA, et al. Methods Find Exp Clin Pharmacol. 1996 Apr;18(3):211-6.