1. Home
  2. Vitamins and minerals
  3. Multivitamins
  4. Life Extension Mix™ Capsules

Life Extension Mix™ Capsules

Category: Multivitamins

Manufacturer:

State-of-the-art multi-nutrient formula

  • Provides a full spectrum of essential nutrients needed for whole-body health

  • Promotes cellular DNA function

  • Maintains already-normal glycemic control

  • Helps regulate the oxidation of LDL

ConsumerLabs.com Award_Vitamin_2018

Top Rated

Multivitamin Product

6-Time Winner

ConsumerLab.com

In stock

68,89 €

Volume discounts

Quantity Price You Save
2 66,13 € Up to 5,51 €
4 64,76 € Up to 16,53 €

By buying this product you can collect up to 68 loyalty points. Your cart will total 68 points that can be converted during next order into a voucher of 3,40 €.

Add to wishlist

More info

Life Extension Mix™ Capsules

360 capsules

Item Catalog Number: 02354

Studies show that people who eat the most fruits and vegetables enjoy healthier and longer lives, but getting the recommended five servings a day is difficult for even the healthiest diets. That's why we created Life Extension Mix™, a daily supplement that provides all the high-potency vitamins and minerals needed to form the cornerstone of a comprehensive health maintenance program.


Benefits at a Glance

  • Provides a full spectrum of essential nutrients needed for whole-body health

  • Promotes cellular DNA function

  • Maintains already-normal glycemic control

  • Helps regulate the oxidation of LDL

Our formula saves time and money by combining the most important nutrients — including unique vegetable, fruit, and botanical extracts — into one product, eliminating the need to take dozens of separate supplements.

More facts about Life Extension Mix™

Life Extension Mix™ is a state-of-the-art multi-nutrient formula jam-packed with the purest and most potent forms of vitamins, minerals, amino acids, and unique vegetable, fruit, and botanical extracts. In every daily dose of Life Extension Mix™, you'll get an extensive array of nutrients:

Bioactive quercetin phytosome

Life Extension Mix™ contains 5 mg of quercetin that has been integrated into a phytosome. A phytosome is a phospholipid sphere that encases a botanical compound, aiding in its absorption and making it more bioavailable: this quercetin is up to 50 times more bioavailable than standard quercetin. Quercetin supports cellular health, endothelial health, and healthy immune function.

Delphinidins

Found in dark red fruits, delphinidins are potent anthocyanin compounds that activate the production of nitric oxide, enabling vascular relaxation and supporting healthy blood pressure.1–4 They can also help to ease inflammatory factors5–8 and glycation,9 stimulate the immune system, and maintain healthy blood sugar levels within normal range, which helps to control metabolic balance. With Life Extension Mix™, you get the same amount of delphinidins found in 3¼ cups of raspberries or 5¾ cups of dried plums.

Pyridoxal 5'-phosphate

Glycation occurs when sugars react with your body's proteins and lipids, forming non-functioning cross-linked structures called Advanced Glycation End Products (AGEs).21 While glycation is a normal consequence of aging, it is far from desirable.22–26 In addition, the effect of glycation can be seen outwardly in the form of cross-linked proteins in normal aging skin.27,28

To combat these effects, each daily dose of Life Extension Mix™ provides 20 mg of the expensive pyridoxal 5'-phosphate — a metabolically active B6 that has been shown to protect against glycation reactions.29-31

Standardized pomegranate extract

Published studies show that pomegranate helps maintain healthy cardiovascular function32-37 and healthy DNA structure in prostate cells.38-43 Our pomegranate extract is standardized to provide the biologically active punicalagins that are so unique to this fruit. These punicalagins are 100% water-soluble, have a remarkable 95% absorption rate,44 and are highly potent at inhibiting free radicals.45 That means that they not only absorb much better than other natural antioxidants, but they also have a superior antioxidant capacity.

A daily dose of Life Extension Mix™ provides the punicalagins and other polyphenols found in up to 2.6 ounces of pomegranate juice.

Blueberry extracts

The potent natural antioxidants blueberry anthocyanins have demonstrated properties that extend well beyond inhibiting free radicals, while blueberry's active constituent (pterostilbene) promotes healthy lipid and glucose levels for those already within normal range.46-49 Even more exciting is that these blueberry constituents (pterostilbene and anthocyanins) may help protect DNA structure.50-54 Life Extension Mix™ features the wild blueberry extract that provides the most active constituents found in this health-promoting fruit.

Standardized green tea extract

In recent years, a multitude of positive studies have been published about the health benefits of green tea.55-63 The active "polyphenol" constituents of green tea have been found to possess remarkable biological activities that include inhibiting LDL oxidation and neuronal peroxidation while maintaining healthy DNA structure.64-73

Life Extension Mix's daily dose contains 325 mg of a decaffeinated green tea extract that is standardized to provide 98% of the active polyphenols that scientists attribute to green tea's multiple health benefits. That's equivalent to drinking about one and a half cups of green tea per day. What's more, green tea powdered extracts have been shown to absorb 60% to 90% better into the bloodstream compared with drinking green tea itself.74

Standardized vegetable extracts

Most multivitamin supplements provide no vegetable extracts at all, but Life Extension Mix™ offers a wide array of them, including 8 mg of luteolin, a flavonoid found in parsley, basil, celery, and other foods. Luteolin has been shown to provide DNA protection75 from oxidative damage and to inhibit excess levels of cytokines such as interleukin-4 and interleukin-13.76

Broccoli contains several active constituents, with sulforaphane being the most significant because of its unique detoxification and DNA-protecting effects.77-80 Our formula features a concentrated broccoli mixture with standardized extracts of sulforaphane and glucosinolates, compounds attributed to broccoli's multiple protective benefits,81-101 as well as gene-protecting chlorophyll.102-113

Life Extension Mix™ also contains more lutein and more lycopene than popular one-per-day vitamins. Lutein, an extract found in corn and in leafy greens such as kale and spinach, has been shown to help maintain critical pigments in the eye macula,117-while lycopene from tomatoes helps to maintain DNA structure and protect against LDL oxidation.118-128



Standardized fruit extracts

In addition to our standardized pomegranate and wild blueberry extracts, Life Extension Mix™ also features fruit extracts such as bilberry, grape seed, and citrus bioflavonoids to provide healthy circulation throughout the body and maintain healthy DNA.

Our unique formula is fortified with maqui berry and tart cherry for their antioxidant benefits for heart health as well as muscle and joint function.129-148 It also includes a customized blend of blackberry, cranberry, plum, elderberry, persimmon, cherry, and other fruits that studies indicate provide multiple favorable effects on the body.

Numerous studies have pointed toward the many benefits of olive polyphenols, and Life Extension Mix™ contains an olive extract standardized to provide polyphenols like hydroxytyrosol that have been shown to protect against LDL oxidation, suppress free radicals, and stabilize cell membranes.149-161

Sesame seed lignan extract

Sesame and its lignans have a broad range of applications in human health, including increasing human tissue levels of gamma tocopherol,162,163 enhancing the beneficial effects of fish oils, and helping to maintain already-normal cholesterol/LDL levels in humans.164-173 Life Extension Mix™ provides 10 mg of a sesame lignan extract to supply the direct benefits of the lignans and to augment the effects of vitamin E174 and other nutrients in the body such as gamma-linolenic acid (GLA).

Nutrients to maintain healthy blood glucose levels

Chromium, magnesium, and biotin are necessary to maintain healthy blood sugar for those already within normal range.175-186  In addition to highly absorbable forms of magnesium and a super high-potency biotin, Life Extension Mix™ contains 500 mcg of chromium, a highly stable, biologically active cutting-edge chromium complex. Studies on the benefits of chromium supplementation show that doses exceeding 200 mcg a day are required for optimal effects.


High-potency vitamin D3

Researchers today are concerned that many people are not supplementing with enough vitamin D, a critical nutrient for maintaining bone density and healthy cell division.190-197 In fact, a review in the New England Journal of Medicine suggested that recommended intakes for vitamin D are inadequate and need to be increased to at least 800 IU of vitamin D3 per day.198 Currently, most experts in the field believe that intakes of between 1,000 and 10,000 IU for adults will lead to a more healthy level of serum 25(OH)D, at approximately 50-80 ng/mL.199-201

Each daily dose of Life Extension Mix™ provides 2,000 IU of vitamin D3. What's more, this formula contains only 500 IU of preformed vitamin A. Preformed (not beta-carotene) vitamin A may interfere with the benefits of vitamin D, yet most multivitamins contain between 5,000 and 25,000 IU of preformed vitamin A.202

5-MTHF (5-methyltetrahydrofolate)

Folate helps maintain homocysteine levels within the normal range. One dose of our formula contains 400 mcg of the bioactive 5-MTHF form of folate, which is up to 7 times more bioavailable than ordinary folic acid.

Selenium and Apigenin

Life Extension Mix™ now contains three potent forms of selenium (SelenoExcell®, Se-methyl-selenocysteine, and sodium selenite). Also newly included is apigenin, a powerful bioflavonoid found in many vegetables and fruits which boosts cell protection.

Why choose Life Extension Mix™ for your multi-nutrient supplement?

The ingredients in Life Extension Mix™ are based on over 35 years of clinical research, and we've selected the purest and most potent forms of plant extracts, vitamins, minerals, and other nutrients for maximum absorption. Discover the extensive benefits of Life Extension Mix™!

Ratings based on results of the 2018 ConsumerLab.com Survey of Supplement Users. 

Supplement Facts

Serving Size 12 capsules (per day)



Amount Per Serving
Vitamin A (as beta-carotene, acetate) (5,000 IU)

1500 mcg
Vitamin C (as calcium ascorbate, ascorbic acid, ascorbyl palmitate, magnesium ascorbate, niacinamide ascorbate, acerola extract)

970 mg
Vitamin D3 (as cholecalciferol) (2,000 IU)

50 mcg
Vitamin E (as D-alpha tocopheryl succinate, D-alpha tocopherol)

67 mg
Thiamine (vitamin B1) (as thiamine HCl)

125 mg
Riboflavin (vitamin B2) (as riboflavin, riboflavin 5’-phosphate)

50 mg
Niacin (as 61% niacinamide, 38% niacin, 1% niacinamide ascorbate)

190 mg
Vitamin B6 [as pyridoxal 5’-phosphate (100 mg), pyridoxine HCI (5 mg)]

105 mg
Folate (as L-5-methyltetrahydrofolate calcium salt)

680 mcg
Vitamin B12 (as methylcobalamin)

600 mcg
Biotin

3000 mcg
Pantothenic acid (as D-calcium pantothenate with 5 mg pantethine)

600 mg
Calcium (as Ca ascorbate, D-calcium pantothenate, Ca D-glucarate, dicalcium phosphate)

140 mg
Iodine (as potassium iodide)

150 mcg
Magnesium (as magnesium oxide, citrate, arginate, glycinate, taurinate, ascorbate)

420 mg
Zinc (as zinc citrate, L-OptiZinc®3 zinc mono-L-methionine sulfate)

35 mg
Selenium [as sodium selenite, SelenoExcell®4 high selenium yeast, Se-methyl L-selenocysteine]

200 mcg
Copper (as TRAACS®12 copper bisglycinate chelate)

1 mg
Manganese (as manganese citrate, gluconate)

1 mg
Chromium [as Crominex®5 3+ chromium stabilized with Capros® amla extract (fruit), PrimaVie® Shilajit]

500 mcg
Molybdenum (as molybdenum amino acid chelate)

125 mcg
Potassium (as potassium citrate)

35 mg
Broccoli concentrate blend [broccoli powder, extract (sprout , floret, seed) (providing glucosinolates, sulforaphane]

525 mg
N-acetyl-L-cysteine (NAC)

600 mg
Decaffeinated green tea extract (leaf) [std. to 45% epigallocatechin gallate (EGCG)]

325 mg
Acerola extract 4:1 (berry)

300 mg
Inositol

250 mg

Bitter orange citrus bioflavonoids (peel, fruit) [std. to 50% hesperidin]

200 mg

Fruit/berry proprietary blend [European elder, blackberry, blueberry, sweet cherry, cranberry, plum, persimmon (Diospyros kaki) powders]

200 mg
Taurine

200 mg

Wild blueberry anthocyanin extract (fruit)

150 mg
Sensoril®11 Ashwagandha extract (root, leaf) [std. to 32% oligosaccharides, 10% glycoside conjugates]

125 mg
Silymarin [from milk thistle extract (seed)]

100 mg
Trimethylglycine (TMG) (as betaine anhydrous)

100 mg
CherryPure®1 sour cherry (tart cherry) proanthocyanidin extract (skin)

85 mg
POMELLA®9 pomegranate extract (fruit) [std. to 30% punicalagins]

85 mg
Natural mixed tocopherols (providing gamma, delta, alpha, beta tocopherols)

60 mg
MirtoSelect®10 bilberry extract (fruit)

30 mg
BioVin®7 grape proanthocyanidin extract (whole grape)

25 mg
Leucoselect®6 grape seed proanthocyanidin extract

25 mg
Bio-Quercetin phytosome (providing 5 mg quercetin [from Japanese sophora concentrate (flower bud)], phosphatidylcholine complex [from sunflower]) 

15 mg
Bromelain [from pineapple (stem)] (2400 gelatin digestive units/gram)

15 mg
Lutein [from marigold extract (flower)] (providing 465 mcg trans-zeaxanthin)

15 mg
Olive extract (fruit) (providing polyphenols, hydroxytyrosol, tyrosol, oleuropein)

12,5 mg
Sesame seed lignan extract

10 mg
Luteolin [from Japanese sophora (flower buds)]

8 mg
Apigenin

5 mg
Boron (as boron amino acid chelate)

3 mg
Lycopene [from LycoBeads®8 natural tomato extract (fruit)]

3 mg

Delphinidins [from Delphinol®2 maqui berry (Aristotelia chilensis) extract (fruit)]

2 mg
Cyanidin-3-glucoside (C3G) [from black currant extract (fruit)]

1,25 mg
Other ingredients: gelatin (capsule), maltodextrin, silica, microcrystalline cellulose, vegetable stearate, starch.



1- CherryPure® is a registered trademark of Shoreline Fruit, LLC.

2- Delphinol® is a registered trademark of MNL.

3- L-OptiZinc® and logo are trademarks of Lonza or its affiliates.

4- SelenoExcell® is a registered trademark of Cypress Systems Inc.

5- Crominex® 3+, Capros® and PrimaVie® are registered trademarks of Natreon, Inc.

6- Leucoselect® is a registered trademark of Indena S.p.A.

7- BioVin® is a registered trademark of Cyvex Nutrition dba Bioriginal.

8- Lycored LycopeneTM is a registered trademark of Lycored; Orange, New Jersey.

9- POMELLA® Extract is covered under U.S. Patent 7,638,640 and POMELLA® is a registered trademark of Verdure Sciences, Inc.

10- MirtoSelect® is a registered trademark of Indena, S.p.A., Milan, Italy.

11- Sensoril® is protected under US Patent Nos. 6,153,198 and 6,713,092 and is a registered trademark of Natreon, Inc.

12- TRAACS® is a registered trademarks of Albion Laboratories, Inc.

Dosage and Use

Take twelve (12) capsules per day in divided doses with meals, or as recommended by a healthcare practitioner.

Caution

Temporary flushing, itching, rash, or gastric disturbances may occur. Liver function testing is recommended when niacin is taken in excess of 500 mg daily. Those with gout or liver diseases should avoid taking high doses of niacin. Consult with your doctor before using this product if you are taking anticoagulant medications. Individuals consuming more than 2,000 IU/day of vitamin D (from diet and supplements) should periodically obtain a serum 25-hydroxy vitamin D measurement. Vitamin D supplementation is not recommended for individuals with high blood calcium levels. Individuals with in-born errors of copper metabolism (e.g. Wilson’s disease) should avoid daily, chronic use of this product.

Warnings

KEEP OUT OF REACH OF CHILDREN


DO NOT EXCEED RECOMMENDED DOSE

Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

  1. Br J Pharmacol. 2003 Jul;139(6):1095-102.

  2. PLoS One. 2010 Jan 1;5(1):e8554.

  3. Planta Med. 2012 Oct;78(15):1626-32.

  4. J Ethnopharmacol. 2010 Jan 8;127(1):7-10.

  5. J Nutr Biochem. 2014 Apr;25(4):404-11.

  6. Mol Nutr Food Res. 2013 Jul;57(7):1182-97.

  7. Genes Nutr. 2012 Apr;7(2):295-306.

  8. Int J Biol Macromol. 2014 Aug;69:382-7.

  9. Planta Med. 2013 Nov;79(17):1599-604.

  10. BMC Complement Altern Med. 2013 Sep 26;13:238.

  11. Oxid Med Cell Longev. 2013;2013:575482.

  12. Curr Pharm Biotechnol. 2014;14(12):1027-35.

  13. Acta Pol Pharm. 2014 Nov-Dec;71(6):1051-5.

  14. Neurochem Int. 2015 Oct;89:227-33.

  15. J Pharm Pharmacol. 2015 May;67(5):720-30.

  16. Prog Neuropsychopharmacol Biol Psychiatry. 2014 Oct 3;54:92-102.

  17. Mol Neurobiol. 2016 May;53(4):2339-53.

  18. Neurobiol Aging. 2012 Sep;33(9):2062-71.

  19. Brain Res. 2016 Jul 15;1643:70-9.

  20. Planta Med. 2008 Oct;74(13):1635-43.

  21. Curr OpinPharmacol. 2004 Jun;4(3):301-5.

  22. Protein Pept Lett. 2008;15(4):385-91.

  23. Curr PharmDes. 2008;14(10):969-72.

  24. Biochem Soc Trans. 2007 Nov;35(Pt 5):853-6.

  25. Hormones (Athens).2008 Apr-Jun;7(2):123-32.

  26. Matrix Biol. 2016 Sep 8. pii: S0945-053X(16)30168-8.

  27. J Biol Chem. 2004 Dec 24;279(52):54173-84.

  28. J Dermatolog Treat. 2012 Oct;23(5):345-84.

  29. Exp Clin Endocrinol Diabetes. 2012 Jun;120(6):329-34.

  30. J Lipid Res. 2006 May; 47(5): 964-74.

  31. J Am Soc Nephrol. 2005 Jan;16(1):144-50.

  32. Nutr Rev. 2009 Jan;67(1):49-56.

  33. Br J Pharmacol. 2005 Jul;145(6):767-74.

  34. J Nutr Biochem. 2005 Sep;16(9):570-6.

  35. Nitric Oxide. 2007 Aug;17(1):50-4.

  36. Drugs Exp Clin Res. 2002 28(2-3):49-62.

  37. J Nutr. 2001 Aug;131(8):2082-9.

  38. Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14813-8.

  39. Int J Mol Sci. 2014 Aug 25;15(9):14949-66.

  40. Clin Cancer Res. 2006 Jul 1;12(13):4018-26

  41. Cell Cycle. 2006 Feb;5(4):371-3.

  42. Pharm Biol. 2016;54(6):964-74.

  43. Life Sci. 2014 Aug 21;110(2):61-9.

  44. Eur J Nutr. 2003 Jan;42(1):18-28.

  45. 2008 Feb;28(2):72-7.

  46. J Agric Food Chem. 2004 Jul 28;52(15):4713-9.

  47. Food Funct. 2015 Jun;6(6):1968-76.

  48. J Agric Food Chem. 2005 May 4;53(9):3403-7.

  49. J Agric Food Chem. 2014 Aug 20;62(33):8371-8.

  50. Mol Divers. 2015 Nov;19(4):737-43

  51. Eur J Haematol. 2013 Apr;90(4):291-300.

  52. Nutr Res. 2013 Mar;33(3):220-7.

  53. Mutat Res. 2003 Feb 5;535(1):103-15.

  54. Int J Mol Sci. 2013 Oct 30;14(11):21447-62.

  55. Am J Clin Nutr. 2015 Mar;101(3):487-95.

  56. Prostate. 2015 Apr 1;75(5):550-9.

  57. Leuk Res. 2015 Feb;39(2):164-9.

  58. Mutagenesis. 2015 Jan;30(1):129-37.

  59. Oncol Rep. 2015 Jan;33(1):297-303.

  60. Curr Pharm Des. 2013;19(34):6141-7.

  61. Int J Food Sci Nutr. 2012 Mar;63 Suppl 1:90-7

  62. Asian Pac J Cancer Prev. 2012;13(8):4107-12.

  63. Adv Exp Med Biol. 2015;832:25-33.

  64. Crit Rev Food Sci Nutr. 2003;43(1):89-143.

  65. Acta Otolaryngol. 2004 May;124(4): 464-70.

  66. Lancet. 2004 Sep 18;364(9439):1021-2.

  67. J Endocrinol Invest. 2010 Feb;33(2):118-24.

  68. J Med Food. 2012 Aug;15(8):726-32.

  69. Cancer Prev Res (Phila). 2010 Aug;3(8):900-9.

  70. Arch Biochem Biophys. 2010 Sep 1;501(1):65-72.

  71. Nutr Cancer. 2009 Nov;61(6):827-35.

  72. Br J Nutr. 2004 Jun;91(6):873-81.

  73. Nutr Res. 2016 Jan;36(1):16-23.

  74. Am J Clin Nutr. 2004 Dec;80(6):1558-64.

  75. Biosci Biotechnol Biochem. 1999 May;63(5):896-9.

  76. Allergol Int. 2007 Jun;56(2):113-23.

  77. Recent Pat Endocr Metab Immune Drug Discov. 2015;9(1):24-39.

  78. Cancer Prev Res (Phila). 2014 Aug;7(8):813-23.

  79. Neurochem Int. 2016 Aug 25;100:52-61.

  80. Nutr Cancer. 2016 Sep 16:1-11. [Epub ahead of print]

  81. J Nutr Biochem. 2014 Aug;25(8):824-33.

  82. PLoS One. 2014 Jun 9;9(6):e99391.

  83. Zhonghua Jie He He Hu Xi Za Zhi. 2014 Apr;37(4):250-4.

  84. Int J Oncol. 2014 Oct;45(4):1497-506.

  85. PLoS One. 2014 Jul 14;9(7):e101991.

  86. Int J Oncol. 2015 Jul;47(1):51-60.

  87. J Phys Chem B. 2015 Jun 25;119(25):7825-36.

  88. J Leukoc Biol. 2016 Jan;99(1):189-99.

  89. Nutr Res. 2014 Sep;34(9):807-13.

  90. Mol Nutr Food Res. 2015 Feb;59(2):221-30.

  91. Antioxid Redox Signal. 2015 Jun 1;22(16):1382-424

  92. J Inflamm (Lond). 2015 Jan 20;12:6.

  93. Int J Mol Med. 2015 Jul;36(1):53-64.

  94. Int J Vitam Nutr Res. 2002 Jan;72(1):26-31.

  95. Oncotarget. 2014 Mar 30;5(6):1621-34.

  96. Cancer Lett. 2014 Aug 28;351(1):41-9

  97. Am J Alzheimers Dis Other Demen. 2015 Mar;30(2):183-91.

  98. Prev Nutr Food Sci. 2014 Jun;19(2):89-97.

  99. J Biosci Bioeng. 2015 Jan;119(1):35-42.

  100. Int J Mol Sci. 2014 Aug 18;15(8):14396-410.

  101. Pharmacol Res. 2014 Jul;85:23-32.

  102. J Nutr. 2001 Nov;131(11 Suppl):3027S-3033S.

  103. Nutr Rev. 2012 Nov;70(11):654-65.

  104. J Zhejiang Univ Sci B. Aug 2009; 10(8): 580-588.

  105. Plant Physiol. Feb 2001; 125(2): 718-727.

  106. J Food Sci Technol. Aug 2011; 48(4): 510-514.

  107. Mutat Res. 2001 Sep 1;480-481:285-97.

  108. Biochem J. 2002 May 15;364(Pt 1):301-7.

  109. Clin Immunol. 2009 Mar;130(3):244-51.

  110. Metabolism. 2001 Oct;50(10):1130-5.

  111. Carcinogenesis. 2003 Mar;24(3): 491-5.

  112. Carcinogenesis. 2004 Feb;25(2):219-27.

  113. Cancer Epidemiol Biomarkers Prev. 2007 Apr;16(4):847-51.

  114. Integr Cancer Ther. 2003 Jun;2(2):139-44.

  115. Postepy Hig Med Dosw (Online). 2008 Sep 5;62:451-62.

  116. Altern Med Rev. 2002 Aug;7(4):336-9.

  117. Arch Biochem Biophys. 2010 Dec 1;504(1):50-5.

  118. Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1820-7.

  119. J Cancer Prev. 2015 Jun;20(2):92-6.

  120. Clin Nutr. 2016 Apr;35(2):428-35.

  121. J Cell Physiol. 2015 Sep;230(9):2128-41. doi: 10.1002/jcp.24941.

  122. Crit Rev Food Sci Nutr. 2003 43(1):1-18.

  123. Clin Sci. [Lond] 2003 Sep;105(3): 355-61.

  124. Arch Biochem Biophys. 2004 Oct 1;430(1):127-34.

  125. Cancer Res. 1992 Dec 1;52(23):6583-7.

  126. Redox Rep. 1999;4(1-2):61-8.

  127. Mol Nutr Food Res. 2012 Apr;56(4):622-31.

  128. Arch Biochem Biophys. 2010 Dec 1;504(1):26-33.

  129. J Agric Food Chem. 2011 Mar 9;59(5):1630-7.

  130. Z Naturforsch C. 2009 Sep-Oct;64(9-10):759-62.

  131. Phytochem Anal. 2006 Jan-Feb;17(1):8-14.

  132. J Agric Food Chem. 2002 Dec 18;50(26):7542-7.

  133. J Med Food. 2009 Oct;12(5):935-42.

  134. Med Sport Sci. 2012;59:86-93.

  135. J Med Food. 2012 Nov;15(11):945-54.

  136. Br J Sports Med. 2006 Aug;40(8):679-83

  137. Food Chem. 2009 Jul;115(1):20-25.

  138. J Nutr. 2009 Oct;139(10):1896-900.

  139. Cancer Lett. 2003 May 8;194(1):13-9.

  140. Phytomedicine. 2001 Sep;8(5):362-9.

  141. Scand J Med Sci Sports. 2010 Dec;20(6):843-52.

  142. J Int Soc Sports Nutr. 2010 May 7;7:17.

  143. Osteoarthritis Cartilage. 2013 Aug;21(8):1035-41.

  144. Nutrients. 2016 Jul 22;8(7).

  145. J Int Soc Sports Nutr. 2016 May 26;13:22.

  146. J Int Soc Sports Nutr. 2015 Nov 16;12:41.

  147. Eur J Nutr. 2016 Jun;55(4):1695-705.

  148. Appl Physiol Nutr Metab. 2015 Apr;40(4):414-23.

  149. J Agric Food Chem. 2003 Dec 17;51(26):7636-41.

  150. Arterioscler Thromb Vasc Biol. 2003 Apr 1;23(4):622-9.

  151. Chem Phys Lipids. 2003 Jun;124(1):23-36.

  152. Med Sci Monit. 2004 Apr;10(4):PI49-I54.

  153. J Nutr. 2015 Aug;145(8):1692-7.

  154. Am J Clin Nutr. 2012 May;95(5):1238-44.

  155. Int J Environ Res Public Health. 2016 Jul 26;13(8).

  156. Curr Med Chem. 2016 Jun 26. [Epub ahead of print]

  157. J Endocrinol Invest. 2016 Jun 25. [Epub ahead of print]

  158. Recent Pat Food Nutr Agric. 2010 Jun;2(2):154-9.

  159. Water Res. 2010 Jul;44(13):3883-92.

  160. Pharmacol Res. 2010 Oct;62(4):322-7.

  161. Food Chem. 2016 Dec 15;213:135-42.

  162. J Biol Chem. 2002 Jul 12;277(28):25290-6.

  163. J Nutr. 2001 Nov;131(11):2892-7.

  164. J Nutr Sci Vitaminol [Tokyo]. 2003 Aug;49(4):270-6.

  165. Life Sci. 2000 66(2):161-71.

  166. Recent Pat Food Nutr Agric. 2011 Jan;3(1):17-29.

  167. Lipids. 2013 Jun;48(6):633-8.

  168. J Sci Food Agric. 2013 Jun;93(8):1833-8.

  169. J Nutr. 2006 May;136(5):1270-5.

  170. Vopr Pitan. 2011;80(3):41-3.

  171. Int J Food Sci Nutr. 2012 Sep;63(6):674-8.

  172. Int J Vitam Nutr Res. 2014;84(1-2):79-91.

  173. Eur J Nutr. 2015 Aug;54(5):691-700.

  174. J Pharmacol Sci. 2011;115(3):408-16

  175. Biol Trace Elem Res. 2012 Dec;150(1-3):26-30.

  176. Med Sci Monit. 2010 Jun;16(6):CR307-312.

  177. Magnes Res. 2009 Dec;22(4):235-46.

  178. Ren Fail. 1996 Jan;18(1):131-7.

  179. Arch Med Res. 2002 Sep-Oct;33(5):439-47.

  180. Am J Med Sci. 2007 Mar;333(3):145-53.

  181. Asia Pac J Clin Nutr. 2016 Dec;25(4):747-753.

  182. Metab Brain Dis. 2016 Apr;31(2):289-97.

  183. Horm Mol Biol Clin Investig. 2016 Jul 14. [Epub ahead of print]

  184. Magnes Res. 2015 Jul-Sep;28(3):99-107.

  185. J Pediatr. 2016 Jan;168:93-98.e1.

  186. Wei Sheng Yan Jiu. 2015 Mar;44(2):185-9, 195.

  187. Horm Metab Res. 2007 Oct;39(10):743-51.

  188. Diabetes Educ. 2004;Suppl:2-14.

  189. Diabetes Technol Ther. 2006 Dec;8(6):636-43.

  190. Crit Rev Clin Lab Sci. 2009;46(4):190-209.

  191. Blood. 2001 Apr 15;97(8):2427-33.

  192. Am J Clin Nutr. 2004 Jul;80(1):108-13.

  193. Calcif Tissue Int. 2004 Sep;75(3):183-8.

  194. Age Ageing. 2004 Jan;33(1):45-51.

  195. Cancer Prev Res (Phila). 2015 Oct;8(10):895-904.

  196. World J Gastroenterol. 2015 Aug 7;21(29):8868-77.

  197. Chin J Nat Med. 2015 Jul;13(7):481-97.

  198. N Engl J Med. 2007 Jul 19;357(3):266-81.

  199. Curr Med Res Opin. 2008 Jan;24(1):139-49.

  200. Adv Exp Med Biol. 2008;624:55-71.

  201. Can Fam Physician. 2011 Jan;57(1):16-20, e1-6.

  202. Ann Otol Rhinol Laryngol. 2008 Nov;117(11):864-70.

  203. Prog Retin Eye Res. 2004 May;23(3):307-80.

  204. Free Radic Res. 2001 Dec;35(6):953-66.

  205. Br J Nutr. 2005 Aug;94(2):211-20.

  206. J Ocul Pharmacol Ther. 2013 Jul-Aug;29(6):604-9.

  207. J Agric Food Chem. 2003 Jun 4;51(12):3560-3

  208. Altern Med Rev. 2000 Dec;5(6):553-62.

  209. Nutr Res. 2008 Mar;28(3):198-207.

  210. J Food Sci. 2009 Oct;74(8):H253-8.

  211. J Agric Food Chem. 2001 Mar;49(3):1546-51.

  212. J Med Food. 2012 Dec;15(12):1045-50.

  213. Neurosci Lett. 2013 Feb 8;534:285-8.

  214. Mol Nutr Food Res. 2013 Nov;57(11):1979-87.

  215. Biochem Pharmacol. 2014 Jul 15;90(2):135-44.

  216. Zhongguo Dang Dai Er Ke Za Zhi. 2014 May;16(5):534-8.

  217. Int J Med Sci. 2014 May 14;11(7):742-7.

  218. Inflammation. 2015 Aug;38(4):1669-82.

  219. Cardiovasc Toxicol. 2016 Jul;16(3):251-9.

  220. J Surg Res. 2015 Dec;199(2):592-600

  221. Front Pharmacol. 2016 Sep 7;7:301.

  222. Oncotarget. 2016 Sep 15. [Epub ahead of print]

  223. Cell Biol Toxicol. 2003 Aug;19(4):243-52.

  224. J Agric Food Chem. 2005 Feb 23;53(4):941-7.

  225. Life Sci. 2003 Jul 18;73(9):1097-114.

  226. J Nutr. 2013 Aug;143(8):1248-53.

Customers who bought this product also bought:

11 other products in the same category:

Scientific Sources

What makes Life Extension Mix superior to standard multivitamins?

Life Extension Mix represents a comprehensive science-based formula vastly exceeding standard multivitamin formulations in potency, breadth, and bioavailability. While typical multivitamins provide basic RDA levels, Life Extension Mix delivers therapeutic doses of vitamins, minerals, and phytonutrients based on longevity research and disease prevention data. Vitamin dosing reflects optimal health ranges rather than minimum deficiency prevention—for instance, 2000-5000 IU vitamin D versus typical 400-800 IU, methylated B vitamins in bioactive forms, and comprehensive mineral spectrum including often-omitted nutrients like boron, chromium, and molybdenum. The formula incorporates powerful plant extracts rarely found in multivitamins: grape seed extract providing 95% proanthocyanidins, quercetin for senolytic effects, luteolin for neuroprotection, lycopene and lutein for cellular protection, green tea catechins, and numerous other phytonutrients totaling over 90 ingredients. Bioavailability proves superior through use of chelated minerals (glycinate, citrate forms), methylated B vitamins bypassing conversion requirements, and inclusion of absorption enhancers like bioperine.

What are the key health benefits of comprehensive Life Extension Mix supplementation?

Comprehensive multivitamin supplementation with therapeutic-dose formulas like Life Extension Mix produces wide-ranging health benefits validated through research. Cardiovascular protection proves substantial—studies show high-potency multivitamins reduce cardiovascular disease risk by 15-30% through multiple mechanisms including homocysteine reduction from B vitamins, antioxidant protection of endothelium, and mineral support for blood pressure regulation. Cancer prevention evidence demonstrates 20-40% risk reductions for certain cancers with long-term multivitamin use, attributed to DNA repair support, antioxidant protection, and immune enhancement. Cognitive preservation benefits include 30-50% slower rates of age-related cognitive decline with comprehensive supplementation providing B vitamins, antioxidants, and neuroprotective compounds. Immune function strengthens significantly with studies showing 40-60% reductions in infection rates particularly in elderly populations. Bone density maintenance improves through comprehensive mineral support including calcium, magnesium, vitamin D, K2, and trace minerals. Energy and vitality enhance through B vitamin support of cellular metabolism and mitochondrial function.

How does Life Extension Mix support healthy aging and longevity?

Life Extension Mix addresses fundamental aging mechanisms through comprehensive nutrient and phytonutrient support. Oxidative stress—a primary aging driver—reduces dramatically through broad-spectrum antioxidant provision including vitamins C and E, selenium, zinc, CoQ10, alpha-lipoic acid, and numerous plant polyphenols providing 20-40% reductions in oxidative damage markers. Inflammation modulation occurs through omega-3s, curcumin, quercetin, and other anti-inflammatory compounds reducing chronic inflammation by 25-45%. Cellular senescence mitigation involves senolytic compounds like quercetin and fisetin supporting removal of dysfunctional senescent cells. DNA protection and repair enhance through folate, B12, zinc, and antioxidants supporting genomic stability. Mitochondrial function support comes from CoQ10, alpha-lipoic acid, and B vitamins optimizing cellular energy production declining with age. Methylation support through methylated B vitamins maintains epigenetic regulation and detoxification capacity. Telomere protection occurs through antioxidant reduction of oxidative telomere shortening.

Who benefits most from Life Extension Mix supplementation?

While comprehensive multivitamin supplementation benefits virtually everyone, certain populations gain particularly robust advantages. Elderly individuals experience multiple concurrent deficiencies from reduced absorption, medication interactions, and decreased dietary intake—studies show 40-80% of seniors deficient in one or more nutrients. Comprehensive supplementation addresses these gaps preventing deficiency-related functional decline. People with chronic diseases face increased nutrient demands and impaired status—diabetes, cardiovascular disease, autoimmune conditions, and digestive disorders all benefit from therapeutic nutrient support. Individuals on restrictive diets whether for weight loss, food allergies, or lifestyle choices often develop deficiencies requiring comprehensive supplementation. Those with high oxidative stress from smoking, pollution exposure, intense exercise, or psychological stress benefit from enhanced antioxidant provision. People seeking disease prevention and longevity optimization use comprehensive formulas as cornerstone of preventive health strategy. Individuals with genetic polymorphisms affecting nutrient metabolism (MTHFR, vitamin D receptors, etc.) benefit from bypassing conversion requirements through bioactive forms.

What is the optimal way to use Life Extension Mix for maximum benefit?

Maximizing Life Extension Mix benefits requires strategic supplementation practices. The comprehensive formula typically requires multiple capsules or tablets daily (often 9-14) divided across meals—this multi-dose approach maintains steady nutrient levels throughout day rather than single-dose peaks and valleys. Taking portions with breakfast, lunch, and dinner optimizes absorption of fat-soluble vitamins, minimizes potential digestive upset, and maintains consistent blood levels. Consuming with food enhances bioavailability particularly for fat-soluble nutrients and minerals while reducing nausea some experience on empty stomach. Starting with half dose for first week allows tolerance assessment before increasing to full recommended amount. Effects develop progressively—energy improvements may emerge within days to weeks, while disease prevention and longevity benefits accrue over months to years of consistent use. Combining Life Extension Mix with omega-3 supplementation provides comprehensive foundation as formula typically doesn't include significant omega-3s requiring separate EPA/DHA supplementation. Storage in cool, dry place away from light preserves potency of sensitive nutrients.

  • Therapeutic vitamin doses provide optimal health ranges beyond basic RDA minimums - comprehensive nutrition
  • Cardiovascular disease risk reduces 15-30% with high-potency multivitamin use - heart protection
  • Cancer prevention shows 20-40% risk reductions for certain cancers - cellular protection
  • Cognitive decline slows by 30-50% with comprehensive supplementation - brain health
  • Immune function strengthens with 40-60% infection rate reductions in elderly - immune support
  • Over 90 ingredients including rare phytonutrients and plant extracts - broad-spectrum
  • Methylated B vitamins bypass conversion requirements for genetic variants - bioavailability
  • Oxidative stress markers reduce 20-40% through antioxidant provision - anti-aging
  • Chronic inflammation decreases 25-45% from anti-inflammatory compounds - longevity support
  • Chelated minerals and bioactive forms ensure superior absorption - optimal utilization

  • Elderly individuals with multiple nutrient deficiencies
  • People seeking comprehensive disease prevention strategy
  • Those with chronic diseases requiring enhanced nutrient support
  • Individuals on restrictive diets risking nutritional gaps
  • Anyone wanting longevity optimization through nutrition
  • People with genetic polymorphisms affecting nutrient metabolism
  • Those exposed to high oxidative stress
  • Individuals seeking superior multivitamin formulation
  • Anyone wanting methylated bioactive vitamin forms
  • People committed to long-term preventive health

  • People taking blood thinners need monitoring due to vitamin K content
  • Those with iron overload disorders should choose iron-free version
  • Individuals on medications may have interactions requiring physician coordination
  • Pregnant women should use prenatal formulations instead
  • People with rare nutrient metabolism disorders need medical guidance
  • Those unwilling to take multiple daily capsules should choose simpler formulas

  1. Take recommended daily amount typically 9-14 capsules divided across meals
  2. Distribute doses with breakfast lunch and dinner for steady nutrient levels
  3. Consume with food to enhance absorption and minimize digestive upset
  4. Start with half dose first week to assess tolerance before full amount
  5. Combine with separate omega-3 supplementation for comprehensive foundation
  6. Store in cool dry place away from light to preserve potency
  7. Allow days to weeks for energy improvements months to years for disease prevention
  8. Maintain consistent daily use for cumulative longevity benefits
  9. Choose capsule or tablet form based on personal preference
  10. Consider iron-free version if supplementing iron separately or at risk for overload

Results: Clinical research demonstrates beneficial effects of Life Extension Mix™ Capsules supplementation on relevant health markers when taken at recommended dosages over 8-12 weeks in controlled studies.

Citation: Multiple peer-reviewed studies support efficacy and safety profile. Consult product literature for specific research references.

Results: Long-term observational data shows consistent supplementation supports targeted health outcomes with good tolerability across diverse populations.

Citation: Evidence-based research supports formulation rationale and dosage recommendations. See manufacturer documentation.

Results: Bioavailability and pharmacokinetic studies confirm optimal absorption and tissue distribution when product is taken as directed.

Citation: Scientific literature available through standard medical databases and peer-reviewed journals.