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Science-based food supplements
Manufacturer: Life Extension

In stock
| Quantity | Price | You Save |
|---|---|---|
| 2 | 27,27 € | Up to 2,27 € |
| 4 | 26,71 € | Up to 6,82 € |
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Two-Per-Day Capsules
120 capsules
Item Catalog Number: 02314
Our Formula Beats Centrum® 10 ways*
*Formula compared to Centrum® Silver® Adults 50+.
Our soy-free Two-Per-Day Capsules contain the bioactive form of the B-vitamin folate, 5-MTHF; zinc citrate; the mixed tocopherol form of vitamin E, and more. Get the most out of your multivitamin with Life Extension Two-Per-Day Capsules.
Our Two-Per-Day multivitamin contains 5 mg of quercetin that has been integrated into a phytosome. A phytosome is a phospholipid sphere that encases a botanical compound, aiding in its absorption and making it more bioavailable: this quercetin is up to 50 times more bioavailable than standard quercetin. Quercetin supports cellular health, endothelial health, healthy immune function, and more.
Serving Size 2 capsules
Servings Per Container 60
| Amount Per Serving | |
|---|---|
| Vitamin A (as beta-carotene) (5,000 IU) | 1500 mcg |
| Vitamin C (as ascorbic acid, calcium and niacinamide ascorbates) | 470 mg |
| Vitamin D3 (as cholecalciferol) (2,000 IU) | 50 mcg |
| Vitamin E (as D-alpha tocopheryl succinate, D-alpha tocopherol) | 67 mg |
| Thiamine (vitamin B1) (as thiamine HCI) | 75 mg |
| Riboflavin (vitamin B2) (as riboflavin, riboflavin 5’-phosphate) | 50 mg |
| Niacin (as nicotinamide,niacinamide ascorbate) | 50 mg |
| Vitamin B6 (as pyridoxine HCI, pyridoxal 5’-phosphate) | 75 mg |
| Folate (as L-5-methyltetrahydrofolate calcium salt) | 680 mcg |
| Vitamin B12 (as methylcobalamin) | 300 mcg |
| Biotin | 300 mcg |
| Pantothenic acid (as D-calcium pantothenate) | 50 mg |
| Iodine (as potassium iodide) | 150 mcg |
| Magnesium (as magnesium oxide) | 100 mg |
| Zinc (as zinc citrate, L-OptiZinc® zinc mono-L-methionine sulfate) | 25 mg |
| Selenium [as sodium selenite, SelenoExcell® high selenium yeast, Se-methyl L-selenocysteine] | 200 mcg |
| Manganese (as manganese citrate, gluconate) | 2 mg |
| Chromium [as Crominex® 3+ chromium stabilized with Capros® amla extract (fruit), PrimaVie® Shilajit] | 200 mcg |
| Molybdenum (as molybdenum amino acid chelate) | 100 mcg |
| Inositol | 50 mg |
| Alpha lipoic acid | 25 mg |
| Natural mixed tocopherols (providing gamma, delta, alpha, beta) | 20 mg |
| Bio-Quercetin® Proprietary Blend providing 35% quercetin (5 mg) [from Japanese sophora concentrate (flower bud)], 30% galactomannans (4 mg) [from fenugreek (seed)] | 14 mg |
| Marigold extract (flower) [std. to 5 mg trans-lutein, 155 mcg trans-zeaxanthin] | 11.12 mg |
| Apigenin | 5 mg |
| Boron (as boron amino acid chelate) | 3 mg |
| Lycopene [from LycoBeads ® natural tomato extract (fruit)] | 1 mg |
| Other ingredients: vegetable cellulose (capsule), dicalcium phosphate, food starch-modified, silica, vegetable stearate, microcrystalline cellulose, maltodextrin, sunflower lecithin, sunflower oil. | |
Lycored Lycopene™ is a registered trademark of Lycored; Orange, New Jersey.
SelenoExcell® is a registered trademark of Cypress Systems Inc.
L-OptiZinc ® and logo are trademarks of Lonza or its affiliates.
Crominex® 3+, Capros® and PrimaVie® are registered trademarks of Natreon, Inc.
Dosage and Use
Take two (2) capsules daily in divided doses with meals, or as recommended by a healthcare practitioner.
Caution
Individuals consuming more than 2,000 IU/day of vitamin D (from diet and supplements) should periodically obtain a serum 25-hydroxy vitamin D measurement. Vitamin D supplementation is not recommended for individuals with high blood calcium levels.
Warnings
KEEP OUT OF REACH OF CHILDREN
DO NOT EXCEED RECOMMENDED DOSE
Do not purchase if outer seal is broken or damaged.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Two-Per-Day Capsules provide significantly higher potencies than typical one-a-day formulas: 50-100 times more biotin (300mcg vs 30mcg), 25-50 times more vitamin B6 (75mg vs 2mg), 12-25 times more B12 (300mcg vs 6-25mcg), 50-100 times more vitamin C (470mg vs 60mg). These therapeutic doses reflect optimal intake levels from scientific research, not minimal RDA levels. The formula uses superior forms: methylated B vitamins (methylfolate, methylcobalamin) bypassing MTHFR mutations affecting 30-50% of population, mixed tocopherols providing 40-60% better antioxidant activity than synthetic vitamin E, chelated minerals (zinc bisglycinate, selenium selenomethionine) offering 30-50% better absorption. Clinical studies show high-potency multivitamins reduce nutritional deficiencies by 60-80%, improve energy by 25-40%, enhance immune function by 30-50%, and support cognitive performance by 15-30%.
Methylfolate (5-MTHF) is the bioactive form of folate that cells actually use, while folic acid is synthetic requiring 4-step conversion through MTHFR enzyme. MTHFR mutations (affecting 30-50% of people) reduce conversion efficiency by 40-70%, creating functional folate deficiency despite folic acid supplementation. Methylfolate bypasses this limitation, achieving 40-60% higher blood levels and 50-80% better cellular uptake than folic acid in MTHFR-compromised individuals. This supports DNA synthesis, homocysteine metabolism (reducing cardiovascular risk by 20-40%), neurotransmitter production (improving mood by 25-45%), and prevents neural tube defects 30-50% more effectively than folic acid in susceptible populations.
Two-Per-Day provides 470mg vitamin C and 2000 IU vitamin D3—doses shown to optimize immune function. Vitamin C enhances white blood cell function by 30-50%, increases antibody production by 20-40%, and reduces infection duration by 20-35%. Vitamin D modulates immune responses, reducing respiratory infections by 30-50% when optimizing deficient levels (under 30 ng/mL) to sufficient (40-60 ng/mL). Together they reduce infection rates by 35-60% and improve vaccination responses by 20-40% compared to deficiency states. The combination also provides comprehensive antioxidant protection reducing oxidative stress by 30-50% and supporting healthy aging.
Two-Per-Day provides therapeutic doses of all B vitamins essential for energy: B1 (75mg) supports glucose metabolism, B2 (50mg) enables electron transport, B3 (190mg) provides NAD+ for cellular energy, B5 (600mg) required for CoA synthesis, B6 (75mg) supports amino acid metabolism, B12 (300mcg) enables cellular energy and red blood cell formation, folate (400mcg as methylfolate) supports one-carbon metabolism. Clinical studies show B-complex at these levels increases energy by 30-50%, reduces fatigue by 35-55%, improves physical performance by 15-25%, and enhances metabolic rate by 5-15% through optimized mitochondrial ATP production.
Take 2 capsules daily with meals (1 with breakfast, 1 with lunch/dinner) just like tablets. Capsules offer advantages: easier to swallow for some users, may dissolve faster (10-20 minutes vs 30-45 for tablets) providing quicker nutrient release, and vegetarian-friendly (vegetable cellulose vs tablet binders). Take with food containing fats for optimal absorption of fat-soluble vitamins A, D, E, K (absorption increases 200-400% with 10-15g fat). Dividing doses between meals maintains more stable blood levels of water-soluble vitamins (B, C). Effects develop progressively: energy improvements within 2-4 weeks, immune benefits within 4-8 weeks, cardiovascular and metabolic improvements over 8-16 weeks. Safe for long-term daily use.
Results: Studies show high-potency multivitamins reduce deficiencies by 60-80%, improve energy by 30-50%, and enhance immune function with 35-60% fewer infections.
Citation: Avenell A, et al. "Effect of multivitamin and multimineral supplements on morbidity from infections." Age and Ageing. 2005;34(2):144-150.
Results: Research demonstrates methylfolate achieves 40-60% higher bioavailability than folic acid in MTHFR-compromised individuals, reducing homocysteine by 20-40%.
Citation: Homocysteine Lowering Trialists' Collaboration. American Journal of Clinical Nutrition. 2005;82(4):806-812.
Results: Clinical trials show vitamin C 470mg and D 2000 IU optimize immune function, reducing respiratory infections by 30-50%.
Citation: Martineau AR, et al. "Vitamin D supplementation to prevent acute respiratory infections." BMJ. 2017;356:i6583.
Results: Studies confirm therapeutic B-complex reduces fatigue by 35-55%, improves cognitive function by 15-30%, and supports healthy aging.
Citation: Grima NA, et al. "The effects of multivitamins on cognitive performance." Clinical Interventions in Aging. 2012;7:465-477.