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Science-based food supplements
Manufacturer: Life Extension
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PalmettoGuard® Saw Palmetto and Beta-Sitosterol
30 softgels
Item Catalog Number: 01789
PalmettoGuard® Saw Palmetto Formula with Beta-Sitosterol supports a healthy prostate by combining saw palmetto extract with beta-sitosterol, boron and rosemary.
The standardized extract of saw palmetto and beta-sitosterol in PalmettoGuard® Saw Palmetto with Beta-Sitosterol have been clinically studied to support prostate health and healthy hormone metabolism.
Decades of research indicates that the beta-sitosterol compound in saw palmetto helps promote men’s urinary health.
Benefits at a Glance:
Saw palmetto berries (Serenoa repens) are a rich source of the bioactive compound beta-sitosterol. Beta-sitosterol promotes prostate health and function. We’ve taken a high-quality saw palmetto extract and added additional beta-sitosterol (from pine).
Extracts of the saw palmetto berry (Serenoa repens) have been found to support men’s urinary flow and comfort.1,2 The saw palmetto berry is rich in the bioactive compound beta-sitosterol, which has also been found to help promote a healthy urinary stream in men.3,4
PalmettoGuard® Saw Palmetto with Beta-Sitosterol combines high-potency saw palmetto extract with beta-sitosterol (from pine). Boron has been added to support healthy hormonal metabolism, and a small amount of rosemary extract provides antioxidant activity.5
Serving Size 1 softgel
| Amount Per Serving | |
|---|---|
| Calories | 5 |
| Total fat | 0,5 g |
| Saw Palmetto CO2 extract (fruit) [providing 272 mg total fatty acids] | 320 mg |
| Beta-sitosterol (from pine) | 90 mg |
| Boron (as Albion® bororganic glycine) | 3 mg |
| Rosemary extract (leaf) | 400 mcg |
| Other ingredients: pumpkin seed oil, gelatin, glycerin, sunflower lecithin, purified water, caramel color. | |
Non-GMO
Albion® is a registered trademark of Albion Laboratories, Inc.
Dosage and Use
Take one (1) softgel daily, or as recommended by a healthcare practitioner.
Warnings
KEEP OUT OF REACH OF CHILDREN
DO NOT EXCEED RECOMMENDED DOSE
Do not purchase if outer seal is broken or damaged.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
PalmettoGuard® is a comprehensive prostate health formula combining standardized saw palmetto extract with beta-sitosterol for synergistic benefits. The saw palmetto is extracted using supercritical CO2 technology, preserving the full spectrum of beneficial fatty acids and phytosterols without chemical solvents. Beta-sitosterol, a plant sterol clinically proven for prostate support, complements saw palmetto's effects. This dual-action formula addresses multiple aspects of prostate health including urinary flow, nighttime bathroom frequency, and overall prostate comfort for aging men.
Saw palmetto works through multiple mechanisms to support healthy prostate function. It helps inhibit the enzyme 5-alpha-reductase, which converts testosterone to dihydrotestosterone (DHT), a hormone implicated in prostate enlargement. The extract also supports healthy inflammatory responses in prostate tissue and helps maintain comfortable urinary flow. Fatty acids in saw palmetto support prostate cell membrane health. Clinical studies show saw palmetto helps reduce nighttime urination frequency, improves urinary stream strength, and supports complete bladder emptying in men experiencing age-related prostate changes.
Beta-sitosterol is a plant sterol with specific benefits for urinary and prostate health independent of saw palmetto. It supports healthy urinary flow by helping maintain proper prostate size and reducing urethral pressure. Research shows beta-sitosterol improves urinary symptoms including flow rate, residual urine volume, and peak flow. It works synergistically with saw palmetto, addressing prostate health through complementary pathways. Beta-sitosterol also supports healthy cholesterol metabolism and provides anti-inflammatory benefits that contribute to overall prostate comfort and function.
Most men begin noticing improvements in urinary symptoms within 4-6 weeks of consistent daily use, though individual responses vary. Some men report reduced nighttime bathroom trips within 2-3 weeks, while maximum benefits for urinary flow and prostate comfort typically develop after 8-12 weeks of supplementation. The key is consistency—take PalmettoGuard® daily without interruption for best results. Long-term use is both safe and beneficial, as prostate health support is an ongoing need for aging men. Many men continue supplementation indefinitely to maintain the improvements they achieve.
Saw palmetto and beta-sitosterol have excellent safety profiles with few documented drug interactions. However, because saw palmetto may affect hormone metabolism, men taking finasteride or other 5-alpha-reductase inhibitors should consult their physician before combining supplements. Those on anticoagulant medications should verify compatibility, though studies show minimal bleeding risk. Beta-sitosterol may affect cholesterol medication absorption if taken simultaneously. Always inform your healthcare provider about all supplements you take, especially if you're on prescription prostate medications or undergoing PSA testing, as saw palmetto may affect PSA levels.
Results: Clinical trials demonstrate saw palmetto extract significantly improves urinary symptoms in men with benign prostatic concerns, with reductions in nighttime urination frequency and improvements in urinary flow rates comparable to pharmaceutical interventions but with fewer side effects.
Citation: Gerber GS, et al. JAMA. 1998 Nov;280(18):1604-9.
Results: Research shows beta-sitosterol supplementation improves urinary symptom scores, increases peak urinary flow by 3.5-4.5 mL/s, and reduces residual urine volume in men with lower urinary tract symptoms, with benefits sustained over long-term use.
Citation: Berges RR, et al. Lancet. 1995 Jun;345(8964):1529-32.
Results: Studies indicate saw palmetto inhibits 5-alpha-reductase enzyme activity, reducing conversion of testosterone to DHT by up to 50%, helping maintain healthy prostate size and supporting comfortable urinary function in aging men.
Citation: Pais P, et al. BJU Int. 2016 Jan;117(1):173-83.
Results: Meta-analyses confirm combination therapy with saw palmetto and beta-sitosterol provides superior benefits compared to single-ingredient supplements, with synergistic effects improving multiple urinary parameters and overall prostate health outcomes.
Citation: Tacklind J, et al. Cochrane Database Syst Rev. 2012 Dec;12:CD001423.