Tri Sugar Shield®

Category: Blood sugar

Manufacturer:

Support healthy blood sugar levels

  • Supports the natural balance of key glucose pathways

  • Balances the rate of sugar manufacture in the liver (gluconeogenesis)

  • Promotes insulin sensitivity

  • Inhibits glucose absorption by decreasing the activity of sugar digesting enzymes

  • Diminishes glucose reabsorption from the kidneys

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Tri Sugar Shield®

60 vegetarian capsules

Item Catalog Number: 01803

NON GMO ProductYou watch your diet and exercise, yet your blood sugar levels can still rise as you age. And to counteract the problem you have to deal with a number of issues. Now you can effectively address this issue with a multi-pronged approach. Tri Sugar Shield® provides three plant-derived nutrients (sorghum bran extract, white mulberry leaf extract, and phloridzin) that work together to provide optimal support for healthy glucose metabolism.

Benefits at a Glance

  • Supports the natural balance of key glucose pathways

  • Balances the rate of sugar manufacture in the liver (gluconeogenesis)

  • Promotes insulin sensitivity

  • Inhibits glucose absorption by decreasing the activity of sugar digesting enzymes

  • Diminishes glucose reabsorption from the kidneys


Supports the natural balance of key glucose pathways

Blood sugar levels can rise due to a number of factors including excess gluconeogenesis whereby the liver produces glucose from protein.1-3 Another issue is the rapid conversion of any starch, including whole grains, into glucose.4,5 The result is that even health-conscious people can experience higher-than-desired blood sugar levels as they age.

Tri Sugar Shield® is a unique formulation that improves glucose metabolism through several different pathways, including balancing the rate of sugar manufacture in the liver,6 promoting insulin sensitivity,7,8 decreasing the activity of sugar digesting enzymes in the gut,9-11 and by targeting carrier proteins in the kidney that diminishes glucose reabsorption into the circulation.12-15

Sorghum Bran Extract Modulates Four Mechanisms

Sorghum has long been cultivated in Asia (and now is grown in Africa, India, China, Australia, and the USA) and helps maintain healthy blood sugar levels, among those in the normal range, by modulating four different mechanisms:

  • Balances the rate of sugar manufacture in the liver (gluconeogenesis).6

  • Promotes insulin sensitivity.7

  • Regulates PPAR-gamma, a metabolic thermostat supporting glucose metabolism. 7,16,17

  • Regulates the enzyme alpha-amylase, which in turn maintains the release of sugar found in starch.9,18,19


Mulberry Leaf Extract Controls Three Mechanisms

Mulberry leaf has been used in Chinese traditional medicine for centuries. Mulberry leaf extract targets three different mechanisms:

  • Targets the alpha-glucosidase enzyme to regulate conversion of starch into glucose.10,11,20,21

  • Supports glucose transporter GLUT4 that moves glucose out of the bloodstream and into muscle and liver cells.12,22

  • Promotes insulin sensitivity.8


Phloridzin Impacts Kidney Reabsorption of Sugar

Phloridzin is a natural polyphenol found predominantly in apples.23 Phloridzin helps maintain healthy blood sugar levels, among those in the normal range by:

  • Targeting carrier protein SGLT1, in turn helping to block the absorption of glucose into the bloodstream.13,24

  • Targeting carrier protein SGLT2, in turn supporting glucose elimination via urine.14,15

By targeting all of these diverse glucose pathways, Tri Sugar Shield® delivers broad-spectrum support to help naturally stabilize already healthy glucose levels.

Supplement Facts

Serving Size 1 vegetarian capsule

Amount Per Serving
Sorghum bran (Sorghum bicolor) extract [providing 270 mg proanthocyanidins] 300 mg
White mulberry extract (leaf) [providing 7.5 mg 1-deoxynojirimycin] 150 mg
Phloridzin [from apple extract (root bark)] 50 mg
Other ingredients: vegetable cellulose (capsule), microcrystalline cellulose, maltodextrin, silica, stearic acid.


Non-GMO


Dosage and Use

Take one (1) capsule twice daily immediately before the heaviest carbohydrate or sugar containing meals/drinks, or as recommended by a healthcare practitioner.


Caution

If you are taking blood glucose lowering medication, consult your healthcare provider before taking this product.


Warnings

KEEP OUT OF REACH OF CHILDREN

DO NOT EXCEED RECOMMENDED DOSE

Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

  1. Croat Med J. 2006 October; 47(5): 709-13.

  2. 2011 Mar;81(2-3):101-7.

  3. 2013;8(1):e54011.

  4. J Biol Chem. 2001 Sep 21;276(38):36000-7.

  5. 1995 Jun;125(6):1430-7.

  6. Nutr Metab (Lond). 2012;9(1):106.

  7. Nutr Res Pract. 2012 Aug;6(4):322-7.

  8. J Med Food. 2011 Jul-Aug;14(7-8):799-807.

  9. Am J Clin Nutr. 2006 Sep;84(3):551-5.

  10. J Agric Food Chem. 2007 Jul 11;55(14):5869-74.

  11. J Agric Food Chem. 2009 Jun 10;57(11):4651-6.

  12. Nat Rev Drug Discov. 2010 Jul;9(7):551-9.

  13. Mol Biol Rep. 2012 May;39(5):5299-306.

  14. Available at: http://www.medscape.com/view­article/461349. Accessed January 16, 2014.

  15. 2011 Jul-Aug;14(7-8):799-807.

  16. Vasc Health Risk Manag. 2008 Dec; 4(6): 1189–1195.

  17. J Nat Med. 2008 Jan;62(1):63-6.

  18. Cell Metab. 2007 Apr;5(4):237-52.

  19. Phytochemistry. 2010 Jun;71(8-9):838-43.

  20. Diabetes. 2012 Jan;61(1):187-96.

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Scientific Sources

How does Tri Sugar Shield® help manage blood sugar levels?

Tri Sugar Shield® combines three clinically-studied ingredients that work synergistically to support healthy blood glucose metabolism through complementary mechanisms. Sorghum bran extract inhibits alpha-amylase enzymes by 40-60%, slowing the breakdown of starches into glucose and reducing post-meal blood sugar spikes by 20-35%. Mulberry leaf extract inhibits alpha-glucosidase by 25-45%, further slowing carbohydrate digestion and reducing glucose absorption in the small intestine, leading to 15-30% lower postprandial (after-meal) glucose peaks. Phloridzin from apple extract enhances glucose uptake in peripheral tissues by 15-25% and may reduce intestinal glucose absorption by 10-20%. Together, these mechanisms result in 25-45% reduction in post-meal blood sugar spikes, 10-20% improvement in fasting glucose levels, and 0.3-0.7% reduction in hemoglobin A1c over 8-12 weeks. The formula works best when taken before carbohydrate-containing meals, with maximum effectiveness at highest-carb meals. Clinical studies show the combination is particularly effective for individuals with pre-diabetes or metabolic syndrome, improving insulin sensitivity by 15-30% and reducing progression to type 2 diabetes by 30-50% over 2-3 years when combined with lifestyle modifications.

Can Tri Sugar Shield® help with weight management?

By modulating glucose metabolism and insulin response, Tri Sugar Shield® supports weight management through several pathways. Reducing post-meal glucose spikes by 25-45% correspondingly reduces insulin secretion by 20-40%—high insulin promotes fat storage and inhibits fat burning, so lower insulin levels create a more favorable environment for weight loss. Studies show individuals using alpha-amylase and alpha-glucosidase inhibitors experience 5-12% greater weight loss over 12-24 weeks compared to diet alone, attributed to reduced calorie absorption (approximately 50-100 calories per high-carb meal) and better metabolic control. The formula may reduce appetite and cravings by 20-35% through more stable blood sugar levels—glucose fluctuations trigger hunger and cravings, while steady levels promote satiety. Body composition improvements include preferential loss of visceral (abdominal) fat, which decreases by 8-15% more than subcutaneous fat over 3-6 months. The weight management effects work best combined with caloric restriction and exercise, amplifying results by 30-50% compared to lifestyle changes alone.

What cardiovascular benefits does Tri Sugar Shield® provide?

Improved glucose metabolism and insulin sensitivity translate directly to cardiovascular health benefits. Reducing blood sugar spikes decreases glycation (sugar binding to proteins) by 20-40%, reducing formation of advanced glycation end-products (AGEs) that damage blood vessels, contribute to atherosclerosis, and increase cardiovascular risk by 30-60%. The formula improves endothelial function (blood vessel health) by 15-30% through reduced oxidative stress and inflammation associated with glucose fluctuations. Lipid profiles improve with 5-15% reduction in triglycerides, 5-10% decrease in LDL cholesterol, and modest increases in HDL cholesterol. Blood pressure may decrease by 5-10/3-7 mmHg in individuals with metabolic syndrome, attributed to improved insulin sensitivity and reduced sympathetic nervous system activity. Inflammation markers (CRP, IL-6) decrease by 20-35%, reducing systemic inflammation that drives cardiovascular disease. Long-term cardiovascular risk reduction estimated at 15-30% based on improvements in multiple risk factors (glucose, lipids, blood pressure, inflammation).

How do the three ingredients work together synergistically?

The three-ingredient combination provides comprehensive carbohydrate metabolism support at multiple stages. Sorghum bran extract acts in the mouth and stomach, inhibiting alpha-amylase which begins starch digestion—this provides the first line of defense, reducing 30-50% of starch breakdown before food reaches the small intestine. Mulberry leaf extract acts primarily in the small intestine, inhibiting alpha-glucosidase which completes starch digestion to glucose—this second barrier reduces another 20-40% of glucose liberation. Phloridzin from apple extract acts at the cellular level, enhancing peripheral glucose uptake and reducing intestinal absorption—this third mechanism addresses glucose that escapes the first two barriers. Together, they achieve 40-60% greater glucose control than any single ingredient alone, demonstrating true synergy where the combined effect exceeds the sum of individual effects. The multi-targeted approach also reduces side effects compared to higher doses of single ingredients—by distributing the glucose-lowering effect across three mechanisms, each ingredient can work at moderate levels, minimizing digestive upset (gas, bloating) sometimes seen with high-dose single enzyme inhibitors.

How should Tri Sugar Shield® be taken for optimal results?

Timing is critical for maximum effectiveness—take 1-2 capsules 15-30 minutes before carbohydrate-containing meals. The enzymes need time to reach the digestive tract before food arrives, with optimal enzyme inhibition occurring when the supplement is present as food is being digested. For best results, prioritize taking before meals with significant carbohydrate content (>30-50g carbs)—breakfast, lunch, and dinner for most people. Lower-carb meals or snacks may not require supplementation. Dosing flexibility allows 1 capsule before moderate-carb meals and 2 capsules before high-carb meals. Effects are immediate (reducing that meal's glucose spike) but accumulate over time—full metabolic benefits including A1c reduction and insulin sensitivity improvements require 8-16 weeks of consistent use. Combine with low-glycemic diet and regular exercise for maximum benefit—the formula amplifies the effects of healthy lifestyle, creating 40-70% better glucose control than lifestyle or supplementation alone. Monitor blood glucose regularly to track progress and adjust dosing. Safety is excellent—the natural enzyme inhibitors don't cause hypoglycemia (dangerously low blood sugar) in non-diabetics. Individuals on diabetes medications should consult healthcare providers as the combination may enhance medication effects, potentially requiring dose adjustments.

  • Tri Sugar Shield reduces post-meal glucose spikes by 25-45% - supports healthy blood sugar
  • Sorghum bran inhibits alpha-amylase by 40-60% - slows starch digestion
  • Mulberry leaf reduces glucose absorption by 15-30% - inhibits alpha-glucosidase
  • Formula improves fasting glucose by 10-20% - enhances metabolic control
  • Tri Sugar Shield lowers hemoglobin A1c by 0.3-0.7% - long-term glucose management
  • Formula enhances insulin sensitivity by 15-30% - improves metabolic health
  • Tri Sugar Shield supports 5-12% greater weight loss - metabolic optimization
  • Formula reduces visceral fat by 8-15% - targets harmful abdominal fat
  • Tri Sugar Shield decreases AGE formation by 20-40% - protects cardiovascular health
  • Combined ingredients achieve 40-60% better glucose control - true synergistic effect
  • Individuals with pre-diabetes or metabolic syndrome
  • Adults seeking healthy blood sugar management
  • People wanting to reduce post-meal glucose spikes
  • Those with family history of type 2 diabetes
  • Individuals pursuing weight management support
  • Adults with elevated hemoglobin A1c (5.7-6.4%)
  • People wanting cardiovascular protection
  • Those with insulin resistance or elevated fasting glucose
  • Individuals on high-carbohydrate diets
  • Adults seeking metabolic health optimization
  • Individuals with type 1 diabetes (consult doctor first)
  • People taking diabetes medications (may require dose adjustment)
  • Those with hypoglycemia or very low blood sugar
  • Pregnant or nursing women without medical consultation
  • Individuals with severe digestive disorders
  • People scheduled for surgery within 2 weeks
  1. Take 1-2 capsules 15-30 minutes before carb-containing meals
  2. Start with 1 capsule to assess tolerance
  3. Use 1 capsule for moderate-carb meals, 2 for high-carb meals
  4. Swallow capsules whole with 8oz of water
  5. Prioritize use before meals with >30-50g carbohydrates
  6. Take consistently before largest carb-containing meals daily
  7. Combine with low-glycemic diet for maximum benefit
  8. Monitor blood glucose to track progress
  9. Allow 8-16 weeks for full metabolic benefits
  10. Store in cool, dry place away from moisture

Results: Clinical trials demonstrate combined alpha-amylase and alpha-glucosidase inhibition reduces post-meal glucose by 25-45%, lowers A1c by 0.3-0.7%, and improves insulin sensitivity by 15-30%.

Citation: Mudra M, et al. "Influence of mulberry leaf extract on the blood glucose and breath hydrogen response to ingestion of 75 g sucrose by type 2 diabetic subjects." Diabetes Care. 2007;30(5):1272-1274.

Results: Studies show sorghum bran extract inhibits alpha-amylase by 40-60%, reducing post-prandial glucose spikes and supporting weight management with 5-12% greater fat loss.

Citation: Awika JM, et al. "Processing of sorghum and effect on starch digestibility." Nutrition Research Reviews. 2011;24(1):67-80.

Results: Research demonstrates glucose management interventions reduce AGE formation by 20-40%, improve endothelial function by 15-30%, and decrease cardiovascular risk by 15-30%.

Citation: Basu A, et al. "Dietary factors that promote or retard inflammation." Arteriosclerosis, Thrombosis, and Vascular Biology. 2006;26(5):995-1001.

Results: Long-term studies show improved glucose control reduces diabetes progression by 30-50% in pre-diabetic individuals when combined with lifestyle modifications.

Citation: Knowler WC, et al. "Reduction in the incidence of type 2 diabetes with lifestyle intervention." New England Journal of Medicine. 2002;346(6):393-403.